Literature DB >> 12884016

Detection of glial fibrillary acidic protein and neurofilaments in the cerebrospinal fluid of patients with neurocysticercosis.

J Luis Quintanar1, Luis Manuel Franco, Eva Salinas.   

Abstract

Neurocysticercosis (NCC) is an infection caused by Taenia solium larval metacestodes in the central nervous system. The glial fibrillary acidic protein (GFAP) and neurofilaments (NFs) can be used as markers of glial and neuronal damage, respectively. We studied the GFAP and NFs of 68, 160 and 200 kDa in the cerebrospinal fluid (CSF) of patients with NCC by Western blotting. Our results showed that patients with NCC had significantly elevated GFAP levels in the CSF compared with the control, whereas NFs of 68, 160 and 200 kDa were not detected in the CFS of NCC patients. We concluded that GFAP could be used as a marker of glial damage in the CFS of NCC patients.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 12884016     DOI： 10.1007/s00436-003-0850-5

Source DB:  PubMed          Journal:  Parasitol Res        ISSN： 0932-0113            Impact factor:   2.289


  11 in total

1.  Enzyme linked immunosorbent assay (ELISA) for the detection of IgG, IgM, IgE and IgA against Cysticercus cellulosae in cerebrospinal fluid of patients with neurocysticercosis.

Authors:  Newton Satoru Odashima; Osvaldo Massaiti Takayanagui; José Fernando de Castro Figueiredo
Journal:  Arq Neuropsiquiatr       Date:  2002-06       Impact factor: 1.420

2.  CSF neurofilament and glial fibrillary acidic protein in normal pressure hydrocephalus.

Authors:  M Tullberg; L Rosengren; E Blomsterwall; J E Karlsson; C Wikkelsö
Journal:  Neurology       Date:  1998-04       Impact factor: 9.910

3.  Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

Authors:  H Towbin; T Staehelin; J Gordon
Journal:  Proc Natl Acad Sci U S A       Date:  1979-09       Impact factor: 11.205

4.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

5.  Astroglial and neuronal proteins in cerebrospinal fluid as markers of CNS involvement in Lyme neuroborreliosis.

Authors:  L Dotevall; L Hagberg; J E Karlsson; L E Rosengren
Journal:  Eur J Neurol       Date:  1999-03       Impact factor: 6.089

Review 6.  Proposed diagnostic criteria for neurocysticercosis.

Authors:  O H Del Brutto; V Rajshekhar; A C White; V C Tsang; T E Nash; O M Takayanagui; P M Schantz; C A Evans; A Flisser; D Correa; D Botero; J C Allan; E Sarti; A E Gonzalez; R H Gilman; H H García
Journal:  Neurology       Date:  2001-07-24       Impact factor: 9.910

7.  Increased cerebrospinal fluid levels of neurofilament protein in progressive supranuclear palsy and multiple-system atrophy compared with Parkinson's disease.

Authors:  B Holmberg; L Rosengren; J E Karlsson; B Johnels
Journal:  Mov Disord       Date:  1998-01       Impact factor: 10.338

8.  Patients with amyotrophic lateral sclerosis and other neurodegenerative diseases have increased levels of neurofilament protein in CSF.

Authors:  L E Rosengren; J E Karlsson; J O Karlsson; L I Persson; C Wikkelsø
Journal:  J Neurochem       Date:  1996-11       Impact factor: 5.372

9.  Neurofilament protein levels in CSF are increased in dementia.

Authors:  L E Rosengren; J E Karlsson; M Sjögren; K Blennow; A Wallin
Journal:  Neurology       Date:  1999-03-23       Impact factor: 9.910

10.  Neurofilament protein in cerebrospinal fluid: a potential marker of activity in multiple sclerosis.

Authors:  J N Lycke; J E Karlsson; O Andersen; L E Rosengren
Journal:  J Neurol Neurosurg Psychiatry       Date:  1998-03       Impact factor: 10.154
View more
  2 in total

1.  Cerebrospinal fluid (CSF) neuronal biomarkers across the spectrum of HIV infection: hierarchy of injury and detection.

Authors:  Julia Peterson; Magnus Gisslen; Henrik Zetterberg; Dietmar Fuchs; Barbara L Shacklett; Lars Hagberg; Constantin T Yiannoutsos; Serena S Spudich; Richard W Price
Journal:  PLoS One       Date:  2014-12-26       Impact factor: 3.240

Review 2.  Host immune responses during Taenia solium Neurocysticercosis infection and treatment.

Authors:  Ulrich Fabien Prodjinotho; Jakobo Lema; Matthew Lacorcia; Veronika Schmidt; Nermina Vejzagic; Chummy Sikasunge; Bernard Ngowi; Andrea Sylvia Winkler; Clarissa Prazeres da Costa
Journal:  PLoS Negl Trop Dis       Date:  2020-04-16
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.