Literature DB >> 12882549

Microbial transformation of ginsenoside Rb1 by Rhizopus stolonifer and Curvularia lunata.

Aling Dong1, Min Ye, Hongzhu Guo, Junhua Zheng, Dean Guo.   

Abstract

Of 49 microbial strains screened for their capabilities to transform ginsenoside Rb1, Rhizopus stolonifer and Curvularia lunata produced four key metabolites: 3-O-[beta-D-glucopyranosyl-(1,2)-beta-D-glucopyranosyl]-20-O-[beta-D-glucopyranosyl]-3beta,12beta, 20(S)-trihydroxydammar-24-ene (1), 3-O-[beta-D-glucopyranosyl-(1,2)-beta-D-glucopyranosyl]-20-O-[beta-D-glucopyranosyl]-3beta,12beta, 20(S)-trihydroxydammar-24-ol (2), 3-O-[beta-D-glucopyranosyl-(1,2)-beta-D-glucopyranosyl]-3beta, 12beta, 20(S)-trihydroxydammar-24-ene (3), and 3-O-beta-D-glucopyranosyl-3beta, 12beta, 20(S)-trihydroxydammar-24-ene (4), identified by TOF-MS, 1H- and 13C-NMR spectral data. Metabolites 1, 3 and 4 were from the incubation with R. stolonifer, and 1 and 2 from the incubation with C. lunata. Compound 2 was identified as a new compound.

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Year:  2003        PMID: 12882549     DOI: 10.1023/a:1022320824000

Source DB:  PubMed          Journal:  Biotechnol Lett        ISSN: 0141-5492            Impact factor:   2.461


  13 in total

1.  Co-transformation of Panax major ginsenosides Rb₁ and Rg₁ to minor ginsenosides C-K and F₁ by Cladosporium cladosporioides.

Authors:  Lunpeng Wu; Yan Jin; Chengri Yin; Longlv Bai
Journal:  J Ind Microbiol Biotechnol       Date:  2012-01-20       Impact factor: 3.346

Review 2.  Genome sequencing of strain Cellulosimicrobium sp. TH-20 with ginseng biotransformation ability.

Authors:  Fei Zheng; Wei Zhang; Xiaodan Chu; Yulin Dai; Jing Li; Huanxi Zhao; Liankui Wen; Hao Yue; Shanshan Yu
Journal:  3 Biotech       Date:  2017-07-11       Impact factor: 2.406

Review 3.  Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: An update for 2003-2004.

Authors:  David J Harvey
Journal:  Mass Spectrom Rev       Date:  2009 Mar-Apr       Impact factor: 10.946

4.  Microbial transformation of ginsenoside Rb1 to compound K by Lactobacillus paralimentarius.

Authors:  Lin-Hu Quan; Yeon-Ju Kim; Guan Hao Li; Kwang-Tea Choi; Deok-Chun Yang
Journal:  World J Microbiol Biotechnol       Date:  2013-01-22       Impact factor: 3.312

5.  Highly selective biotransformation of ginsenoside Rb1 to Rd by the phytopathogenic fungus Cladosporium fulvum (syn. Fulvia fulva).

Authors:  Xuesong Zhao; Juan Wang; Jie Li; Ling Fu; Juan Gao; Xiuli Du; Hongtao Bi; Yifa Zhou; Guihua Tai
Journal:  J Ind Microbiol Biotechnol       Date:  2009-02-20       Impact factor: 3.346

6.  Enzymatic Transformation of Ginsenoside Rb1 by Lactobacillus pentosus Strain 6105 from Kimchi.

Authors:  Se-Hwa Kim; Jin-Woo Min; Lin-Hu Quan; Sungyoung Lee; Dong-Uk Yang; Deok-Chun Yang
Journal:  J Ginseng Res       Date:  2012-07       Impact factor: 6.060

7.  Characterizing a full spectrum of physico-chemical properties of ginsenosides rb1 and rg1 to be proposed as standard reference materials.

Authors:  Il-Woung Kim; Hee-Do Hong; Sang Yoon Choi; Da-Hye Hwang; Youl Her; Si-Kwan Kim
Journal:  J Ginseng Res       Date:  2011-11       Impact factor: 6.060

8.  Characterizing a full spectrum of physico-chemical properties of (20S)- and (20R)-ginsenoside Rg3 to be proposed as standard reference materials.

Authors:  Il-Woung Kim; Won Suk Sun; Bong-Sik Yun; Na-Ri Kim; Dongsun Min; Si-Kwan Kim
Journal:  J Ginseng Res       Date:  2013-03       Impact factor: 6.060

9.  Biotransformation of Ginsenoside Rb1 to Prosapogenins, Gypenoside XVII, Ginsenoside Rd, Ginsenoside F2, and Compound K by Leuconostoc mesenteroides DC102.

Authors:  Lin-Hu Quan; Jin-Ying Piao; Jin-Woo Min; Ho-Bin Kim; Sang-Rae Kim; Dong-Uk Yang; Deok Chun Yang
Journal:  J Ginseng Res       Date:  2011-09       Impact factor: 6.060

10.  Pharmacogenomics and the Yin/Yang actions of ginseng: anti-tumor, angiomodulating and steroid-like activities of ginsenosides.

Authors:  Patrick Ying Kit Yue; Nai Ki Mak; Yuen Kit Cheng; Kar Wah Leung; Tzi Bun Ng; David Tai Ping Fan; Hin Wing Yeung; Ricky Ngok Shun Wong
Journal:  Chin Med       Date:  2007-05-15       Impact factor: 5.455

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