OBJECTIVE: To validate the 20-meter shuttle walking test (20MST) in the assessment of maximal oxygen consumption (VO(2)max) and maximal speed in patients with coronary artery disease (CAD). DESIGN: Single-sample validity study. SETTING: Cardiac rehabilitation service in France. PARTICIPANTS: Seventeen men with CAD. INTERVENTIONS: Subjects underwent a symptom-limited treadmill test (SLTT) in a laboratory, with a speed starting at 2.5km/h and increasing by 0.5km/h every minute, and performed an adapted 20MST in a corridor, with a speed starting at 3km/h and increasing by 1km/h every minute until exhaustion. MAIN OUTCOME MEASURES: VO(2) measured during the 20MST with the Cosmed K2 telemetric gas analyzer (K2 VO(2)), estimated VO(2) calculated by the Léger equation (Léger VO(2)) from the maximal speed obtained during the 20MST, and VO(2) measured during the SLTT (SLTT VO(2)). Maximal speeds attained on the treadmill and on the 20MST were also compared. RESULTS: A significant (P<.0001) difference was observed between the Léger estimate of VO(2) and those of K2 VO(2) and SLTT VO(2) (mean +/- standard deviation, 12.28+/-5.90mL. min(-1).kg(-1) vs 23.04+/-7.17 and 22.56+/-6.29mL.min(-1).kg(-1)). No difference was found between the treadmill and the 20MST maximal speeds (6.73+/-0.91km/h, 6.78+/-1.23km/h, respectively). Measured with the Cosmed K2, a significant relationship existed between VO(2) and each speed level (r=.95, P<.0001; VO(2)=4.24x speed-7.37, standard estimation error=2.29mL.min(-1).kg(-1)). CONCLUSION: Maximal VO(2) and maximal speed measured on the treadmill did not differ significantly from those obtained on the 20MST. The current 20MST equation (Léger equation) was not valid to estimate VO(2) in CAD patients. A modified prediction equation of VO(2) was given and would need a larger number of patients to be generalized.
OBJECTIVE: To validate the 20-meter shuttle walking test (20MST) in the assessment of maximal oxygen consumption (VO(2)max) and maximal speed in patients with coronary artery disease (CAD). DESIGN: Single-sample validity study. SETTING: Cardiac rehabilitation service in France. PARTICIPANTS: Seventeen men with CAD. INTERVENTIONS: Subjects underwent a symptom-limited treadmill test (SLTT) in a laboratory, with a speed starting at 2.5km/h and increasing by 0.5km/h every minute, and performed an adapted 20MST in a corridor, with a speed starting at 3km/h and increasing by 1km/h every minute until exhaustion. MAIN OUTCOME MEASURES: VO(2) measured during the 20MST with the Cosmed K2 telemetric gas analyzer (K2 VO(2)), estimated VO(2) calculated by the Léger equation (Léger VO(2)) from the maximal speed obtained during the 20MST, and VO(2) measured during the SLTT (SLTT VO(2)). Maximal speeds attained on the treadmill and on the 20MST were also compared. RESULTS: A significant (P<.0001) difference was observed between the Léger estimate of VO(2) and those of K2 VO(2) and SLTT VO(2) (mean +/- standard deviation, 12.28+/-5.90mL. min(-1).kg(-1) vs 23.04+/-7.17 and 22.56+/-6.29mL.min(-1).kg(-1)). No difference was found between the treadmill and the 20MST maximal speeds (6.73+/-0.91km/h, 6.78+/-1.23km/h, respectively). Measured with the Cosmed K2, a significant relationship existed between VO(2) and each speed level (r=.95, P<.0001; VO(2)=4.24x speed-7.37, standard estimation error=2.29mL.min(-1).kg(-1)). CONCLUSION: Maximal VO(2) and maximal speed measured on the treadmill did not differ significantly from those obtained on the 20MST. The current 20MST equation (Léger equation) was not valid to estimate VO(2) in CAD patients. A modified prediction equation of VO(2) was given and would need a larger number of patients to be generalized.
Authors: Andrew W Gardner; Donald E Parker; Polly S Montgomery; Danuta Sosnowska; Ana I Casanegra; Zoltan Ungvari; Anna Csiszar; Sarah X Zhang; Josh J Wang; William E Sonntag Journal: J Clin Transl Endocrinol Date: 2015-12-01