| Literature DB >> 12878136 |
Esther Caballero1, Marta Adeva, Suzanne Calderón, Heidi Sahagún, Fernando Tomé, Manuel Medarde, José Luis Fernández, Miguel López-Lázaro, Maria Jesús Ayuso.
Abstract
An array of 4-(aryl or indolyl)pyrrolo[3,4-c]carbazole-1,3-diones (open analogues of indolocarbazole alkaloids), 10-(aryl or indolyl)pyrrolo[3,4-b]carbazole-1,3-diones, and different derivatives have been prepared using a Diels-Alder plus Fischer indolization approach and tested as cytotoxic agents. Some representative compounds display interesting cytotoxic profiles.Entities:
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Year: 2003 PMID： 12878136 DOI： 10.1016/s0968-0896(03)00308-0
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641