Literature DB >> 12871156

A review of natural and modified betulinic, ursolic and echinocystic acid derivatives as potential antitumor and anti-HIV agents.

I Baglin1, A-C Mitaine-Offer, M Nour, K Tan, C Cavé, M-A Lacaille-Dubois.   

Abstract

The aim of this review is to update current knowledge on the betulinic, ursolic and echinocystic acids and their natural and semisynthetic analogs, focussing on their cytotoxic and anti-HIV activities. Then, the last results of the authors' team on unusual semisynthetic derivatives of these triterpenoids will be presented in order to establish structure/activity relationships.

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Year:  2003        PMID： 12871156     DOI： 10.2174/1389557033487917

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN： 1389-5575            Impact factor:   3.862


  18 in total

1.  New ionic derivatives of betulinic acid as highly potent anti-cancer agents.

Authors:  Challa Suresh; Hua Zhao; Angelique Gumbs; Chellu S Chetty; Himangshu S Bose
Journal:  Bioorg Med Chem Lett       Date:  2011-12-28       Impact factor: 2.823

2.  Microbe-mediate transformation of echinocystic acid by whole cells of filamentous fungus Cunninghamella blakesleana CGMCC 3.910.

Authors:  Shaobin Fu; Xu Feng; Di-An Sun
Journal:  Mol Biol Rep       Date:  2018-09-07       Impact factor: 2.316

3.  Ionic derivatives of betulinic acid as novel HIV-1 protease inhibitors.

Authors:  Hua Zhao; Shaletha S Holmes; Gary A Baker; Suresh Challa; Himangshu S Bose; Zhiyan Song
Journal:  J Enzyme Inhib Med Chem       Date:  2011-10-10       Impact factor: 5.051

4.  Effect of betulinic acid and its ionic derivatives on M-MuLV replication.

Authors:  Jasmine Phillips; Iesha Phillips; Blessing Enya; Hua Zhao; Takayuki Nitta
Journal:  Biochem Biophys Res Commun       Date:  2018-04-21       Impact factor: 3.575

5.  Ionic derivatives of betulinic acid exhibit antiviral activity against herpes simplex virus type-2 (HSV-2), but not HIV-1 reverse transcriptase.

Authors:  Robert J Visalli; Hannah Ziobrowski; Kameswara R Badri; Johnny J He; Xiugen Zhang; Sri Ranjini Arumugam; Hua Zhao
Journal:  Bioorg Med Chem Lett       Date:  2015-06-06       Impact factor: 2.823

6.  Hypoglycemic activity of constituents from Astianthus viminalis in normal and streptozotocin-induced diabetic mice.

Authors:  Rosa Martha Pérez Gutiérrez; Rosario Vargas Solis; Efren Garcia Baez; Yoha Gallardo Navarro
Journal:  J Nat Med       Date:  2009-05-30       Impact factor: 2.343

7.  Valorization of olive tree leaves: Extraction of oleanolic acid using aqueous solutions of surface-active ionic liquids.

Authors:  Ana Filipa M Cláudio; Alice Cognigni; Emanuelle L P de Faria; Armando J D Silvestre; Ronald Zirbs; Mara G Freire; Katharina Bica
Journal:  Sep Purif Technol       Date:  2018-04-16       Impact factor: 7.312

8.  Antimicrobial Constituents of Artemisia afra Jacq. ex Willd. against Periodontal Pathogens.

Authors:  Garland More; Namrita Lall; Ahmed Hussein; Thilivhali Emmanuel Tshikalange
Journal:  Evid Based Complement Alternat Med       Date:  2012-05-30       Impact factor: 2.629

9.  Synergism of ursolic acid derivative US597 with 2-deoxy-D-glucose to preferentially induce tumor cell death by dual-targeting of apoptosis and glycolysis.

Authors:  Jichuang Wang; Zhou Jiang; Liping Xiang; Yuanfang Li; Minrui Ou; Xiang Yang; Jingwei Shao; Yusheng Lu; Lifeng Lin; Jianzhong Chen; Yun Dai; Lee Jia
Journal:  Sci Rep       Date:  2014-05-21       Impact factor: 4.379

10.  A pentacyclic triterpene natural product, ursolic acid and its prodrug US597 inhibit targets within cell adhesion pathway and prevent cancer metastasis.

Authors:  Liping Xiang; Ting Chi; Qiao Tang; Xiang Yang; Minrui Ou; Xiufen Chen; Xiaobo Yu; Jianzhong Chen; Rodney J Y Ho; Jingwei Shao; Lee Jia
Journal:  Oncotarget       Date:  2015-04-20
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