| Literature DB >> 12865402 |
Abstract
The molecular mechanisms underlying the putative role of osteopontin in the chronic inflammatory disease rheumatoid arthritis are unclear. A study in a murine model of arthritis now demonstrates that a specific antibody directed against the exposed osteopontin epitope SLAYGLR is capable of preventing inflammatory cell infiltration in arthritic joints.Entities:
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Year: 2003 PMID: 12865402 PMCID: PMC164297 DOI: 10.1172/JCI19190
Source DB: PubMed Journal: J Clin Invest ISSN: 0021-9738 Impact factor: 14.808