Literature DB >> 12847174

Chlamydia pneumoniae in children with MS: frequency and quantity of intrathecal antibodies.

K Rostasy1, H Reiber, D Pohl, P Lange, A Ohlenbusch, H Eiffert, M Maass, F Hanefeld.   

Abstract

The authors investigated the frequency and quantity of intrathecal antibody synthesis against Chlamydia pneumoniae and the presence of C pneumoniae antigen in 25 children with MS. C pneumoniae genome was present in two children. In seven children an intrathecal synthesis of C pneumoniae antibodies was detected, representing only a small part of the total intrathecal immunoglobulin G, suggesting that this intrathecal synthesis is part of a polyspecific, oligoclonal immune response.

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Year:  2003        PMID： 12847174     DOI： 10.1212/01.wnl.0000070782.27949.f7

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  9 in total

1.  Chlamydophila pneumoniae Infection and Its Role in Neurological Disorders.

Authors:  Carlo Contini; Silva Seraceni; Rosario Cultrera; Massimiliano Castellazzi; Enrico Granieri; Enrico Fainardi
Journal:  Interdiscip Perspect Infect Dis       Date:  2010-02-21

Review 2.  The MRZ reaction as a highly specific marker of multiple sclerosis: re-evaluation and structured review of the literature.

Authors:  S Jarius; P Eichhorn; D Franciotta; H F Petereit; G Akman-Demir; M Wick; B Wildemann
Journal:  J Neurol       Date:  2016-12-22       Impact factor: 4.849

Review 3.  Low intrathecal antibody production despite high seroprevalence of Epstein-Barr virus in multiple sclerosis: a review of the literature.

Authors:  Klemens Ruprecht; Brigitte Wildemann; Sven Jarius
Journal:  J Neurol       Date:  2017-11-02       Impact factor: 4.849

4.  Chlamydia pneumoniae-specific intrathecal oligoclonal antibody response is predominantly detected in a subset of multiple sclerosis patients with progressive forms.

Authors:  Enrico Fainardi; Massimiliano Castellazzi; Carmine Tamborino; Silva Seraceni; Maria Rosaria Tola; Enrico Granieri; Carlo Contini
Journal:  J Neurovirol       Date:  2009-09       Impact factor: 2.643

Review 5.  Does disease-irrelevant intrathecal synthesis in multiple sclerosis make sense in the light of tertiary lymphoid organs?

Authors:  Mickael Bonnan
Journal:  Front Neurol       Date:  2014-03-11       Impact factor: 4.003

6.  Neuroimmunology: Immunoglobulins and the Intrathecal Polyspecific Immune Response in Acute, Subacute and Chronic Neurological Diseases.

Authors:  Hansotto Reiber
Journal:  EJIFCC       Date:  2004-08-31

7.  Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 2: Results from 108 lumbar punctures in 80 pediatric patients.

Authors:  Sven Jarius; Christian Lechner; Eva M Wendel; Matthias Baumann; Markus Breu; Mareike Schimmel; Michael Karenfort; Adela Della Marina; Andreas Merkenschlager; Charlotte Thiels; Astrid Blaschek; Michela Salandin; Steffen Leiz; Frank Leypoldt; Alexander Pschibul; Annette Hackenberg; Andreas Hahn; Steffen Syrbe; Jurgis Strautmanis; Martin Häusler; Peter Krieg; Astrid Eisenkölbl; Johannes Stoffels; Matthias Eckenweiler; Ilya Ayzenberg; Jürgen Haas; Romana Höftberger; Ingo Kleiter; Mirjam Korporal-Kuhnke; Marius Ringelstein; Klemens Ruprecht; Nadja Siebert; Kathrin Schanda; Orhan Aktas; Friedemann Paul; Markus Reindl; Brigitte Wildemann; Kevin Rostásy
Journal:  J Neuroinflammation       Date:  2020-09-03       Impact factor: 8.322

8.  Parvovirus B19 and mumps virus antibodies are major constituents of the intrathecal immune response in European patients with MS and increase the diagnostic sensitivity and discriminatory power of the MRZ reaction.

Authors:  S Jarius; D Wilken; J Haas; K Ruprecht; L Komorowski; B Wildemann
Journal:  J Neurol       Date:  2021-03-26       Impact factor: 4.849

9.  Comparison of neurophysiological and MRI findings of patients with multiple sclerosis using oligoclonal band technique.

Authors:  Hamit Y Ellidag; Esin Eren; Nezahat Erdogan; Sabiha Ture; Necat Yilmaz
Journal:  Ann Neurosci       Date:  2013-10
  9 in total

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