Literature DB >> 12844082

Functional outcome in a contemporary series of major lower extremity amputations.

Mark R Nehler1, Joseph R Coll, William R Hiatt, Judith G Regensteiner, Gabriel T Schnickel, William A Klenke, Pam K Strecker, Michelle W Anderson, Darrell N Jones, Thomas A Whitehill, Shevie Moskowitz, William C Krupski.   

Abstract

PURPOSE: We undertook this study to document the functional natural history of patients undergoing major amputation in an academic vascular surgery and rehabilitation medicine practice.
METHODS: A retrospective review was conducted of consecutive patients undergoing major lower extremity amputation and rehabilitation in a university and Department of Veterans Affairs hospital. Main outcome variables included operative mortality, follow-up, survival, median time to incision healing, secondary operative procedures for wound management, and conversion from below-knee amputation (BKA) to above-knee amputation (AKA). For surviving patients, quality of life was determined by degree of ambulation, eg, outdoors, indoors only, or no ambulation; use of a prosthesis; and independence, eg, community housing or nursing facility.
RESULTS: From August 1997 through March 2002, 154 patients (130 men; median age, 62 years) underwent 172 major amputations, 78 AKA and 94 BKA, because of either critical limb ischemia (87%) or diabetic neuropathy (13%). Thirty-day operative mortality was 10%. Mean follow-up was 14 months. Healing at 100 and 200 days, as determined with the Kaplan-Meier method, was 55% and 83%, respectively, for BKA, and 76% and 85%, respectively, for AKA. Twenty-three BKA and 16 AKA required additional operative revision, and 18 BKA ultimately were converted to AKA. Survival was 78% at 1 year and 55% at 3 years. Function in surviving patients at 10 and 17 months, respectively, was as follows: 21% and 29% of patients ambulated outdoors, 28% and 25% ambulated indoors only, and 51% and 46% of patients were nonambulatory; 32% and 42% of patients used prosthetic limbs; and 17% and 8% of patients who lived in the community before amputation required care in a nursing facility.
CONCLUSIONS: We were surprised to find that vascular patients in a contemporary setting who require major lower extremity amputation and rehabilitation often remain independent despite infrequent prosthesis use and outdoor ambulation. Although any hope for postoperative ambulation in this population requires salvaging the knee joint, because of the morbidity incurred in both wound healing and rehabilitation efforts, aggressive effort should be reserved for selected patients at good risk. Ability to predict ambulation after BKA in the vascular population is poor.

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Year:  2003        PMID: 12844082     DOI: 10.1016/s0741-5214(03)00092-2

Source DB:  PubMed          Journal:  J Vasc Surg        ISSN: 0741-5214            Impact factor:   4.268


  47 in total

1.  Predictors of Receiving a Prosthesis for Adults With Above-Knee Amputations in a Well-Defined Population.

Authors:  Benjamin F Mundell; Hilal Maradit Kremers; Sue Visscher; Kurtis M Hoppe; Kenton R Kaufman
Journal:  PM R       Date:  2015-12-12       Impact factor: 2.298

2.  Preulcerous Risk Situation in Diabetic Foot Syndrome: Proposal for a Simple Ulcer Prevention Score.

Authors:  Stephan Kress; Helmut Anderten; Anja Borck; Guido Freckmann; Lutz Heinemann; Ulrike Holzmüller; Bernd Kulzer; Alexandra Portele; Oliver Schnell; Helga Varlemann; Claudia Zemmrich; Ralf Lobmann
Journal:  J Diabetes Sci Technol       Date:  2020-06-10

3.  Domains that Determine Quality of Life in Vascular Amputees.

Authors:  Bjoern D Suckow; Philip P Goodney; Brian W Nolan; Ravi K Veeraswamy; Patricia Gallagher; Jack L Cronenwett; Larry W Kraiss
Journal:  Ann Vasc Surg       Date:  2015-02-26       Impact factor: 1.466

Review 4.  Endovascular techniques in limb salvage: infrapopliteal angioplasty.

Authors:  Joseph J Naoum; Elias J Arbid
Journal:  Methodist Debakey Cardiovasc J       Date:  2013-04

5.  Impact of amputation level and comorbidities on functional status of nursing home residents after lower extremity amputation.

Authors:  Todd R Vogel; Gregory F Petroski; Robin L Kruse
Journal:  J Vasc Surg       Date:  2014-01-07       Impact factor: 4.268

6.  Rationale and design of the Clinical and Histologic Analysis of Mesenchymal Stromal Cells in AmPutations (CHAMP) trial investigating the therapeutic mechanism of mesenchymal stromal cells in the treatment of critical limb ischemia.

Authors:  S Keisin Wang; Linden A Green; Natalie A Drucker; Raghu L Motaganahalli; Andres Fajardo; Michael P Murphy
Journal:  J Vasc Surg       Date:  2018-02-01       Impact factor: 4.268

Review 7.  The care of transmetatarsal amputation in diabetic foot gangrene.

Authors:  Michele Ammendola; Rosario Sacco; Lucia Butrico; Giuseppe Sammarco; Stefano de Franciscis; Raffaele Serra
Journal:  Int Wound J       Date:  2016-10-03       Impact factor: 3.315

8.  Patient education level affects functionality and long term mortality after major lower extremity amputation.

Authors:  Michael R Corey; Jamii St Julien; Carly Miller; Bryan Fisher; Sara L Cederstrand; William A Nylander; Raul J Guzman; Jeffery B Dattilo
Journal:  Am J Surg       Date:  2012-08-18       Impact factor: 2.565

9.  Geographic variation in Medicare spending and mortality for diabetic patients with foot ulcers and amputations.

Authors:  Michael R Sargen; Ole Hoffstad; David J Margolis
Journal:  J Diabetes Complications       Date:  2012-10-11       Impact factor: 2.852

10.  Preoperative Predictors of 30-Day Mortality and Prolonged Length of Stay after Above-Knee Amputation.

Authors:  Eric S Wise; William G McMaster; Kelly Williamson; Justine E Wergin; Kyle M Hocking; Colleen M Brophy
Journal:  Ann Vasc Surg       Date:  2015-11-23       Impact factor: 1.466

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