Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 From the top down: towards a predictive biology of signalling networks.

Literature DB >> 12837611

From the top down: towards a predictive biology of signalling networks.

Jaroslav Stark¹, Robin Callard, Michael Hubank.

Abstract

True quantitative and predictive biology requires the ability to interpret increasingly complex datasets in new ways to reveal underlying functional interactions. This has come a step closer with two recent articles that describe a 'top-down' modelling approach to reconstructing functional networks from microarray data.

Mesh：

Year: 2003 PMID： 12837611 DOI： 10.1016/S0167-7799(03)00140-9

Source DB: PubMed Journal: Trends Biotechnol ISSN： 0167-7799 Impact factor: 19.536

Keyword Cloud
Cited

11 in total

1. From single genes to co-expression networks: extracting knowledge from barley functional genomics.

Authors: P Faccioli; P Provero; C Herrmann; A M Stanca; C Morcia; V Terzi
Journal: Plant Mol Biol Date: 2005-07 Impact factor: 4.076

2. Paradoxical results in perturbation-based signaling network reconstruction.

Authors: Sudhakaran Prabakaran; Jeremy Gunawardena; Eduardo Sontag
Journal: Biophys J Date: 2014-06-17 Impact factor: 4.033

3. An update on the strategies in multicomponent activity monitoring within the phytopharmaceutical field.

Authors: Johanna M Gostner; Oliver A Wrulich; Marcel Jenny; Dietmar Fuchs; Florian Ueberall
Journal: BMC Complement Altern Med Date: 2012-03-14 Impact factor: 3.659

4. Silence on the relevant literature and errors in implementation.

Authors: Philippe Bastiaens; Marc R Birtwistle; Nils Blüthgen; Frank J Bruggeman; Kwang-Hyun Cho; Carlo Cosentino; Alberto de la Fuente; Jan B Hoek; Anatoly Kiyatkin; Steffen Klamt; Walter Kolch; Stefan Legewie; Pedro Mendes; Takashi Naka; Tapesh Santra; Eduardo Sontag; Hans V Westerhoff; Boris N Kholodenko
Journal: Nat Biotechnol Date: 2015-04 Impact factor: 54.908

5. Reconstruction of extended Petri nets from time series data and its application to signal transduction and to gene regulatory networks.

Authors: Markus Durzinsky; Annegret Wagler; Wolfgang Marwan
Journal: BMC Syst Biol Date: 2011-07-15

10. Functional genomics in chickens: development of integrated-systems microarrays for transcriptional profiling and discovery of regulatory pathways.

Authors: L A Cogburn; X Wang; W Carre; L Rejto; S E Aggrey; M J Duclos; J Simon; T E Porter
Journal: Comp Funct Genomics Date: 2004

From the top down: towards a predictive biology of signalling networks.

1. From single genes to co-expression networks: extracting knowledge from barley functional genomics.

2. Paradoxical results in perturbation-based signaling network reconstruction.

3. An update on the strategies in multicomponent activity monitoring within the phytopharmaceutical field.

4. Silence on the relevant literature and errors in implementation.

5. Reconstruction of extended Petri nets from time series data and its application to signal transduction and to gene regulatory networks.

6. Correction of scaling mismatches in oligonucleotide microarray data.

7. Integrating Bayesian variable selection with Modular Response Analysis to infer biochemical network topology.

Review 8. Applications of genome-scale metabolic reconstructions.

9. Ranked prediction of p53 targets using hidden variable dynamic modeling.

10. Functional genomics in chickens: development of integrated-systems microarrays for transcriptional profiling and discovery of regulatory pathways.