Literature DB >> 12836612

[Cell cycle and checkpoints in oncology: new therapeutic targets].

Yves Pommier1, Kurt W Kohn.   

Abstract

Leland H. Hartwell, Paul M. Nurse et R. Timothy Hunt just received the Nobel price for their discovery of the molecular components of the cell cycle and cell cycle checkpoints. This review is an update of the molecular networks driving the cell cycle and its regulation, and of the importance of this knowledge for understanding the mechanisms driving oncogenesis and therapeutic developments.

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Year:  2003        PMID: 12836612     DOI: 10.1051/medsci/2003192173

Source DB:  PubMed          Journal:  Med Sci (Paris)        ISSN: 0767-0974            Impact factor:   0.818


  6 in total

1.  Effects of STI571 and p27 gene clone on proliferation and apoptosis of K562 cells.

Authors:  Wei Wang; Li-Bo Yao; Xin-Ping Liu; Qi Feng; Zhen-Chuan Shang; Yun-Xin Cao; Bing-Zhong Sun
Journal:  World J Gastroenterol       Date:  2005-04-14       Impact factor: 5.742

Review 2.  DNA damage response pathways and cell cycle checkpoints in colorectal cancer: current concepts and future perspectives for targeted treatment.

Authors:  S Solier; Y-W Zhang; A Ballestrero; Y Pommier; G Zoppoli
Journal:  Curr Cancer Drug Targets       Date:  2012-05       Impact factor: 3.428

3.  Organization of DNA Replication Origin Firing in Xenopus Egg Extracts: The Role of Intra-S Checkpoint.

Authors:  Diletta Ciardo; Olivier Haccard; Hemalatha Narassimprakash; Jean-Michel Arbona; Olivier Hyrien; Benjamin Audit; Kathrin Marheineke; Arach Goldar
Journal:  Genes (Basel)       Date:  2021-08-09       Impact factor: 4.096

4.  Effect of resveratrol on cell cycle proteins in murine transplantable liver cancer.

Authors:  Liang Yu; Zhong-Jie Sun; Sheng-Li Wu; Cheng-En Pan
Journal:  World J Gastroenterol       Date:  2003-10       Impact factor: 5.742

Review 5.  Depicting combinatorial complexity with the molecular interaction map notation.

Authors:  Kurt W Kohn; Mirit I Aladjem; Sohyoung Kim; John N Weinstein; Yves Pommier
Journal:  Mol Syst Biol       Date:  2006-10-03       Impact factor: 11.429

6.  Biological evaluation of novel thiomaltol-based organometallic complexes as topoisomerase IIα inhibitors.

Authors:  Maria S Legina; Juan J Nogueira; Wolfgang Kandioller; Michael A Jakupec; Leticia González; Bernhard K Keppler
Journal:  J Biol Inorg Chem       Date:  2020-03-19       Impact factor: 3.358

  6 in total

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