Literature DB >> 12835671

Curing metastatic cancer: lessons from testicular germ-cell tumours.

John R W Masters1, Beate Köberle.   

Abstract

Most metastatic cancers are fatal. More than 80% of patients with metastatic testicular germ-cell tumours (TGCTs), however, can be cured using cisplatin-based combination chemotherapy. Why are TGCTs more sensitive to chemotherapeutics than most other tumour types? Answers to this question could lead to new treatments for metastatic cancers.

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Year:  2003        PMID: 12835671     DOI: 10.1038/nrc1120

Source DB:  PubMed          Journal:  Nat Rev Cancer        ISSN: 1474-175X            Impact factor:   60.716


  58 in total

1.  Histological evidence for the existence of germ cell tumor cells showing embryonal carcinoma morphology but lacking OCT4 expression and cisplatin sensitivity.

Authors:  Thomas Mueller; Lutz Peter Mueller; Hans-Juergen Holzhausen; Ralf Witthuhn; Peter Albers; Hans-Joachim Schmoll
Journal:  Histochem Cell Biol       Date:  2010-06-08       Impact factor: 4.304

Review 2.  Advances in the treatment of testicular cancer.

Authors:  Hans-Georg Kopp; Markus Kuczyk; Johannes Classen; Arnulf Stenzl; Lothar Kanz; Frank Mayer; Michael Bamberg; Jörg Thomas Hartmann
Journal:  Drugs       Date:  2006       Impact factor: 9.546

3.  Inhibition of experimental metastasis by targeting the HUIV26 cryptic epitope in collagen.

Authors:  Jennifer M Roth; Maresa Caunt; Alexandra Cretu; Abebe Akalu; Desiree Policarpio; Xiaolu Li; Paul Gagne; Silvia Formenti; Peter C Brooks
Journal:  Am J Pathol       Date:  2006-05       Impact factor: 4.307

4.  A bifunctional platinum(II) antitumor agent that forms DNA adducts with affinity for the estrogen receptor.

Authors:  Eunsuk Kim; Peter T Rye; John M Essigmann; Robert G Croy
Journal:  J Inorg Biochem       Date:  2008-10-26       Impact factor: 4.155

Review 5.  Testicular germ cell tumours: predisposition genes and the male germ cell niche.

Authors:  Duncan Gilbert; Elizabeth Rapley; Janet Shipley
Journal:  Nat Rev Cancer       Date:  2011-03-17       Impact factor: 60.716

Review 6.  Male reproductive health and prostate cancer risk.

Authors:  Thomas J Walsh
Journal:  Curr Opin Urol       Date:  2011-11       Impact factor: 2.309

Review 7.  Nanocarriers for delivery of platinum anticancer drugs.

Authors:  Hardeep S Oberoi; Natalia V Nukolova; Alexander V Kabanov; Tatiana K Bronich
Journal:  Adv Drug Deliv Rev       Date:  2013-10-08       Impact factor: 15.470

8.  Identification and validation of a gene expression signature that predicts outcome in adult men with germ cell tumors.

Authors:  James E Korkola; Jane Houldsworth; Darren R Feldman; Adam B Olshen; Li-Xuan Qin; Sujata Patil; Victor E Reuter; George J Bosl; R S K Chaganti
Journal:  J Clin Oncol       Date:  2009-09-21       Impact factor: 44.544

9.  Binding interaction of HMGB4 with cisplatin-modified DNA.

Authors:  Semi Park; Stephen J Lippard
Journal:  Biochemistry       Date:  2012-08-17       Impact factor: 3.162

Review 10.  [Advances in basic research on testicular germ cell tumors : clinical implications].

Authors:  L H J Looijenga
Journal:  Urologe A       Date:  2009-04       Impact factor: 0.639

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