BACKGROUND: Septic shock remains one of the leading causes of mortality in critically ill patients. Optimal management depends on prompt diagnosis with identification of the causative organisms to allow appropriate antibiotic therapy. PATIENT: We report the first case of septic shock caused by Corynebacterium D2, a micro-organism that can cause encrusted cystitis and pyelitis of transplanted kidneys or, more rarely, native kidneys. Diagnosis rests on identification of risk factors, positive urine cultures, and computed tomography results. Despite optimal treatment our patient died with persistent encrusted pyelitis. CONCLUSIONS: Corynebacterium D2 is known to cause chronic inflammation of the bladder and proximal urinary tract but can also cause severe septic shock in immunocompetent patients.
BACKGROUND:Septic shock remains one of the leading causes of mortality in critically illpatients. Optimal management depends on prompt diagnosis with identification of the causative organisms to allow appropriate antibiotic therapy. PATIENT: We report the first case of septic shock caused by Corynebacterium D2, a micro-organism that can cause encrusted cystitis and pyelitis of transplanted kidneys or, more rarely, native kidneys. Diagnosis rests on identification of risk factors, positive urine cultures, and computed tomography results. Despite optimal treatment our patient died with persistent encrusted pyelitis. CONCLUSIONS: Corynebacterium D2 is known to cause chronic inflammation of the bladder and proximal urinary tract but can also cause severe septic shock in immunocompetent patients.
Authors: J M Morales; J M Aguado; R Diaz-Gonzalez; E Salto; A Andres; C Campo; M Praga; M A Martinez; O Leiva; A Rodriguez-Noriega Journal: Transplant Proc Date: 1992-02 Impact factor: 1.066
Authors: P Eschwege; M Hauk; P Blanchet; C Hiesse; A Vieillefond; M Blery; B Charpentier; G Benoit Journal: Transplant Proc Date: 1995-08 Impact factor: 1.066
Authors: J M Aguado; J M Morales; E Salto; C Lumbreras; M Lizasoain; R Diaz-Gonzalez; M A Martinez; A Andres; M Praga; A R Noriega Journal: Transplantation Date: 1993-09 Impact factor: 4.939
Authors: Els Van de Perre; Gina Reichman; Deborah De Geyter; Caroline Geers; Karl M Wissing; Emmanuel Letavernier Journal: Front Med (Lausanne) Date: 2021-01-21
Authors: Hamza Sakhi; Olivier Join-Lambert; Anna Goujon; Thibault Culty; Paul Loubet; Julien Dang; Sylvain Drouot; Hubert de Bayser; Christophe Michaud; Louise Ghislain; Thomas Stehlé; Christophe Legendre; Dominique Joly; Paul Meria; Mohamad Zaidan Journal: Kidney Int Rep Date: 2020-11-04