Literature DB >> 12816448

Chemoselective building blocks for dendrimers from relative reactivity data.

Mackay B Steffensen1, Eric E Simanek.   

Abstract

Competition reactions for the substitution of monochlorotriazines with different amines provide relative reactivity data that can be used to identify new groups for the chemoselective syntheses of dendrimers based on melamine. Target 1 is prepared using a one-pot per generation strategy without protecting group manipulations or functional group interconversions.

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Year:  2003        PMID： 12816448     DOI： 10.1021/ol0347491

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  14 in total

1.  Synthesis of odd generation triazine dendrimers using a divergent, macromonomer approach.

Authors:  Jongdoo Lim; Meredith A Mintzer; Lisa M Perez; Eric E Simanek
Journal:  Org Lett       Date:  2010-03-19       Impact factor: 6.005

2.  Antitumor activity and molecular dynamics simulations of paclitaxel-laden triazine dendrimers.

Authors:  Jongdoo Lim; Su-Tang Lo; Sonia Hill; Giovanni M Pavan; Xiankai Sun; Eric E Simanek
Journal:  Mol Pharm       Date:  2012-02-03       Impact factor: 4.939

3.  Synthesis and characterization of a triazine dendrimer that sequesters iron(III) using 12 desferrioxamine B groups.

Authors:  Jongdoo Lim; Vincent J Venditto; Eric E Simanek
Journal:  Bioorg Med Chem       Date:  2010-05-20       Impact factor: 3.641

4.  Divergent synthesis of triazine dendrimers using a trimethylene-dipiperidine linker that increases efficiency, simplifies analysis, and improves product solubility.

Authors:  Meredith A Mintzer; Lisa M Perez; Eric E Simanek
Journal:  Tetrahedron Lett       Date:  2010-03-31       Impact factor: 2.415

5.  Dendrimers Based on [1,3,5]-Triazines.

Authors:  Mackay B Steffensen; Emily Hollink; Frank Kuschel; Monika Bauer; Eric E Simanek
Journal:  J Polym Sci A Polym Chem       Date:  2006-06-01       Impact factor: 2.702

6.  Identification of Diamine Linkers with Differing Reactivity and their Application in the Synthesis of a Melamine Dendrimers.

Authors:  Karlos X Moreno; Eric E Simanek
Journal:  Tetrahedron Lett       Date:  2008-02-11       Impact factor: 2.415

7.  SYNTHESIS OF 2-[3,3'-DI-(TERT-BUTOXYCARBONYL)-AMINODIPROPYLAMINE]-4,6,-DICHLORO-1,3,5-TRIAZINE AS A MONOMER AND 1,3,5-[TRIS-PIPERAZINE]-TRIAZINE AS A CORE FOR THE LARGE SCALE SYNTHESIS OF MELAMINE (TRIAZINE) DENDRIMERS.

Authors:  Abdellatif Chouai; Vincent J Venditto; Eric E Simanek; Ruth E McDermott; John A Ragan
Journal:  Organic Synth       Date:  2009-01-01

8.  Dendrimers terminated with dichlorotriazine groups provide a route to compositional diversity.

Authors:  Subrata Patra; Brittany Kozura; Adela Y-T Huang; Alan E Enciso; Xiankai Sun; Jer-Tsong Hsieh; Chai-Lin Kao; Hui-Ting Chen; Eric E Simanek
Journal:  Org Lett       Date:  2013-07-19       Impact factor: 6.005

9.  Intercepting the synthesis of triazine dendrimers with nucleophilic pharmacophores: a general strategy toward drug delivery vehicles.

Authors:  Vincent J Venditto; Kimberly Allred; Clinton D Allred; Eric E Simanek
Journal:  Chem Commun (Camb)       Date:  2009-08-11       Impact factor: 6.222

10.  Synthesis of 2,4,6-tri-substituted-1,3,5-triazines.

Authors:  Carlos A M Afonso; Nuno M T Lourenço; Andreia de A Rosatella
Journal:  Molecules       Date:  2006-01-31       Impact factor: 4.411
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