Literature DB >> 12800057

NBI-6024 (Neurocrine Biosciences).

Nick Giannoukakis1.   

Abstract

Neurocrine is developing NBI-6024 in collaboration with Taisho, as part of Neurocrine's altered peptide ligand (APL) program, as a potential treatment for type I diabetes. By July 2002, Neurocrine had completed four phase I/II trials of NBI-6024 and the compound was in phase IIb studies in Europe and phase Ib studies in the US. By October 2002, a second phase IIb trial was scheduled to begin in the US later in 2002 or in early 2003.

Entities:  

Year:  2002        PMID: 12800057

Source DB:  PubMed          Journal:  IDrugs        ISSN: 1369-7056


  2 in total

1.  No effect of the altered peptide ligand NBI-6024 on beta-cell residual function and insulin needs in new-onset type 1 diabetes.

Authors:  Markus Walter; Areti Philotheou; François Bonnici; Anette-G Ziegler; Roland Jimenez
Journal:  Diabetes Care       Date:  2009-08-18       Impact factor: 19.112

2.  Transgenic substitution with Greater Amberjack Seriola dumerili fish insulin 2 in NOD mice reduces beta cell immunogenicity.

Authors:  Kylie S Foo; Alicja A Skowronski; Danielle Baum; Rebuma Firdessa-Fite; Sebastian Thams; Linshan Shang; Rémi J Creusot; Charles A LeDuc; Dieter Egli; Rudolph L Leibel
Journal:  Sci Rep       Date:  2019-03-21       Impact factor: 4.379

  2 in total

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