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Literature DB >> 12797830

Mechanism of free radical oxygenation of polyunsaturated fatty acids by cyclooxygenases.

Carol A Rouzer¹, Lawrence J Marnett.

Abstract

Entities: Chemical

Mesh：

Substances：

Year: 2003 PMID： 12797830 DOI： 10.1021/cr000068x

Source DB: PubMed Journal: Chem Rev ISSN： 0009-2665 Impact factor: 60.622

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85 in total

Review 1. Enzymes of the cyclooxygenase pathways of prostanoid biosynthesis.

Authors: William L Smith; Yoshihiro Urade; Per-Johan Jakobsson
Journal: Chem Rev Date: 2011-09-27 Impact factor: 60.622

2. Two new eicosanoids with a unique isovalerianic acid ester moiety from the South China Sea gorgonian Dichotella gemmacea.

Authors: Chang-Yun Wang; Jie Zhao; Hai-Yan Liu; Chang-Lun Shao; Qing-Ai Liu; Yang Liu; Yu-Cheng Gu
Journal: Lipids Date: 2010-11-16 Impact factor: 1.880

3. Structural comparisons of arachidonic acid-induced radicals formed by prostaglandin H synthase-1 and -2.

Authors: Ah-lim Tsai; Gang Wu; Corina E Rogge; Jian-Ming Lü; Sheng Peng; Wilfred A van der Donk; Graham Palmer; Gary J Gerfen; Richard J Kulmacz
Journal: J Inorg Biochem Date: 2010-11-27 Impact factor: 4.155

4. On the relationships of substrate orientation, hydrogen abstraction, and product stereochemistry in single and double dioxygenations by soybean lipoxygenase-1 and its Ala542Gly mutant.

Authors: Gianguido Coffa; Ann N Imber; Brendan C Maguire; Gurunathan Laxmikanthan; Claus Schneider; Betty J Gaffney; Alan R Brash
Journal: J Biol Chem Date: 2005-09-12 Impact factor: 5.157

Mechanism of free radical oxygenation of polyunsaturated fatty acids by cyclooxygenases.

Review 1. Enzymes of the cyclooxygenase pathways of prostanoid biosynthesis.

2. Two new eicosanoids with a unique isovalerianic acid ester moiety from the South China Sea gorgonian Dichotella gemmacea.

3. Structural comparisons of arachidonic acid-induced radicals formed by prostaglandin H synthase-1 and -2.

4. On the relationships of substrate orientation, hydrogen abstraction, and product stereochemistry in single and double dioxygenations by soybean lipoxygenase-1 and its Ala542Gly mutant.

Review 5. Regulation of intracellular cyclooxygenase levels by gene transcription and protein degradation.

6. Oxyferryl heme and not tyrosyl radical is the likely culprit in prostaglandin H synthase-1 peroxidase inactivation.

Review 7. Control of oxygenation in lipoxygenase and cyclooxygenase catalysis.

8. Long-chain carboxychromanols, metabolites of vitamin E, are potent inhibitors of cyclooxygenases.

Review 9. Cyclooxygenases: structural and functional insights.

10. Coxibs interfere with the action of aspirin by binding tightly to one monomer of cyclooxygenase-1.