| Literature DB >> 12796779 |
Hervé Seitz1, Neil Youngson, Shau-Ping Lin, Simone Dalbert, Martina Paulsen, Jean-Pierre Bachellerie, Anne C Ferguson-Smith, Jérôme Cavaillé.
Abstract
MicroRNAs (miRNAs) are an abundant class of RNAs that are approximately 21-25 nucleotides (nt) long, interact with mRNAs and trigger either translation repression or RNA cleavage (RNA interference, RNAi) depending on the degree of complementarity with their targets. Here we show that the imprinted mouse distal chromosome 12 locus encodes two miRNA genes expressed from the maternally inherited chromosome and antisense to a retrotransposon-like gene (Rtl1) expressed only from the paternal allele.Entities:
Mesh:
Substances:
Year: 2003 PMID: 12796779 DOI: 10.1038/ng1171
Source DB: PubMed Journal: Nat Genet ISSN: 1061-4036 Impact factor: 38.330