Literature DB >> 12790549

A general, Brønsted acid-catalyzed hetero-Michael addition of nitrogen, oxygen, and sulfur nucleophiles.

Tobias C Wabnitz1, Jonathan B Spencer.   

Abstract

[reaction: see text] Strong Brønsted acids such as bis(trifluoromethanesulfon)imide catalyze the hetero-Michael addition of carbamates, alcohols, and thiols to alpha,beta-unsaturated ketones, alkylidene malonates, and acrylimides. Scope, reaction rates, and yields are superior to comparable Lewis acid-catalyzed processes.

Entities:  

Year:  2003        PMID： 12790549     DOI： 10.1021/ol034596h

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Synthesis of novel 4H-pyrimido[1,6-a]pyrimidines via a one-pot three-component condensation.

Authors:  Jinbao Xiang; Hanghang Li; Kai Yang; Lang Yi; Yongnan Xu; Qun Dang; Xu Bai
Journal:  Mol Divers       Date:  2011-12-04       Impact factor: 2.943

2.  L-proline catalyzed Michael additions of thiophenols to alpha,beta-unsaturated compounds, particularly alpha-enones, in the ionic liquid [bmim]PF6.

Authors:  Peter Kotrusz; Stefan Toma
Journal:  Molecules       Date:  2006-03-17       Impact factor: 4.411

3.  Inorganic base-catalyzed formation of antivirally active N-substituted benzamides from α-amido sulfones and N-nucleophile.

Authors:  Yi Jin; Baoan Song; Deyu Hu; Xiangyang Li; Pinaki S Bhadury; Zhenchao Wang; Song Yang
Journal:  Chem Cent J       Date:  2011-05-05       Impact factor: 4.215

Review 4.  Triflamides and Triflimides: Synthesis and Applications.

Authors:  Mikhail Y Moskalik; Vera V Astakhova
Journal:  Molecules       Date:  2022-08-15       Impact factor: 4.927
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.