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Literature DB >> 12783501

HR22C16: a potent small-molecule probe for the dynamics of cell division.

Srinivas Hotha¹, Justin C Yarrow, Janet G Yang, Sarah Garrett, Kishore V Renduchintala, Thomas U Mayer, Tarun M Kapoor.

Abstract

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Year: 2003 PMID： 12783501 DOI： 10.1002/anie.200351173

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

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17 in total

1. Allosteric drug discrimination is coupled to mechanochemical changes in the kinesin-5 motor core.

Authors: Elizabeth D Kim; Rebecca Buckley; Sarah Learman; Jessica Richard; Courtney Parke; David K Worthylake; Edward J Wojcik; Richard A Walker; Sunyoung Kim
Journal: J Biol Chem Date: 2010-03-18 Impact factor: 5.157

2. Mitotic kinesin inhibitors induce mitotic arrest and cell death in Taxol-resistant and -sensitive cancer cells.

Authors: Adam I Marcus; Ulf Peters; Shala L Thomas; Sarah Garrett; Amelia Zelnak; Tarun M Kapoor; Paraskevi Giannakakou
Journal: J Biol Chem Date: 2005-01-13 Impact factor: 5.157

Review 3. Spindle checkpoint function and cellular sensitivity to antimitotic drugs.

Authors: Hiroshi Y Yamada; Gary J Gorbsky
Journal: Mol Cancer Ther Date: 2006-12 Impact factor: 6.261

4. Docking studies on kinesin spindle protein inhibitors: an important cooperative 'minor binding pocket' which increases the binding affinity significantly.

Authors: Cheng Jiang; Yadong Chen; Xiaojian Wang; Qidong You
Journal: J Mol Model Date: 2007-06-23 Impact factor: 1.810

5. Interaction of the mitotic kinesin Eg5 inhibitor monastrol with P-glycoprotein.

Authors: Tanja Peters; Heike Lindenmaier; Walter E Haefeli; Johanna Weiss
Journal: Naunyn Schmiedebergs Arch Pharmacol Date: 2005-12-20 Impact factor: 3.000

6. Dimethylenastron suppresses human pancreatic cancer cell migration and invasion in vitro via allosteric inhibition of mitotic kinesin Eg5.

Authors: Xiao-dong Sun; Xing-juan Shi; Xiao-ou Sun; You-guang Luo; Xiao-jing Wu; Chang-fu Yao; Hai-yang Yu; Deng-wen Li; Min Liu; Jun Zhou
Journal: Acta Pharmacol Sin Date: 2011-10-10 Impact factor: 6.150

Review 7. Kinesins and cancer.

Authors: Oliver Rath; Frank Kozielski
Journal: Nat Rev Cancer Date: 2012-07-24 Impact factor: 60.716