Literature DB >> 17172401

Spindle checkpoint function and cellular sensitivity to antimitotic drugs.

Hiroshi Y Yamada1, Gary J Gorbsky.   

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Year:  2006        PMID: 17172401      PMCID: PMC2596631          DOI: 10.1158/1535-7163.MCT-06-0319

Source DB:  PubMed          Journal:  Mol Cancer Ther        ISSN: 1535-7163            Impact factor:   6.261


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6.  Complete loss of the tumor suppressor MAD2 causes premature cyclin B degradation and mitotic failure in human somatic cells.

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7.  Caspase 3, periodically expressed and activated at G2/M transition, is required for nocodazole-induced mitotic checkpoint.

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