Literature DB >> 1278313

The biliary excretion of [3H] lysergic acid diethylamide in Wistar and Gunn rats.

D J Back, J K Singh.   

Abstract

The biliary excretion of [3H] LSD was studied in Wistar and homozygous Gunn rats. In Wistar rats approximately 46% of the given dose was recovered from bile in 2.5 h whilst in the homozygous Gunn rat 26% was recovered in the same time period. In both strains the main metabolites were glucuronides.

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Year:  1976        PMID： 1278313     DOI： 10.1007/BF01990195

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  16 in total

1.  The fate of lysergic acid di[ 14C]ethlamide ([14-C-A1LSD) in the rat.

Authors:  Z H Siddik; R D Barnes; L G Dring; R L Smith; R T Williams
Journal:  Biochem Soc Trans       Date:  1975       Impact factor: 5.407

2.  THE METABOLITES OF ERGOMETRINE AND LYSERGIC ACID DIETHYLAMIDE IN RAT BILE.

Authors:  M B SLAYTOR; S E WRIGHT
Journal:  J Med Pharm Chem       Date:  1962-05

3.  The metabolism of lysergic acid diethylamide.

Authors:  E S BOYD
Journal:  Arch Int Pharmacodyn Ther       Date:  1959-07-01

4.  The presence of metabolites of 3-H-testosterone in the lumen of the cauda epididymidis of the rat.

Authors:  D J Back
Journal:  Steroids       Date:  1975-03       Impact factor: 2.668

5.  The conjugation of 1- and 2-naphthols and other phenols in the cat and pig.

Authors:  I D Capel; P Millburn; R T Williams
Journal:  Xenobiotica       Date:  1974-10       Impact factor: 1.908

6.  Biliary excretion of 14 C-edrophonium and its glucuronide metabolite in Gunn rats.

Authors:  T N Calvey; D J Back
Journal:  Arch Int Pharmacodyn Ther       Date:  1973-01

7.  Differentiation of homologous forms of hepatic microsomal UDP-glucuronyltransferase. II. Characterization of the bilirubin conjugating form.

Authors:  D A Vessey; J Goldenberg; D Zakim
Journal:  Biochim Biophys Acta       Date:  1973-05-05

8.  Regulation of microsomal enzymes by phospholipids. VI. Abnormal enzyme-lipid interactions in liver microsomes from Gunn rats.

Authors:  D Zakim; J Goldenberg; D A Vessey
Journal:  Biochim Biophys Acta       Date:  1973-02-28

9.  Differences between the biliary excretion of tri [14C] methyl-(3-hydroxy-phenyl) ammonium iodide in Wistar and Gunn rats.

Authors:  T N Calvey; S M Somani; A Wright
Journal:  Biochem J       Date:  1970-10       Impact factor: 3.857

10.  The pharmacokinetics of (14C)-edrophonium in normal wistar rats and homozygous Gunn rats with ligated renal pedicles.

Authors:  D J Back; T N Calvey
Journal:  Br J Pharmacol       Date:  1974-05       Impact factor: 8.739
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