Literature DB >> 1278312

Drug interactions in intestinal absorption of 3H-digitoxin in rats.

W Braun, K H Damm.   

Abstract

The absorption of 3H-digitoxin from perfused rat small intestine was inhibited by probenecid (1.0 x 10-2 M), ethacrynic acid (0.5 x 10-3 M), and mersalyl (8.0 x 10-3 M) indicating that digitoxin absorption is at least partly an active process.

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Year:  1976        PMID： 1278312     DOI： 10.1007/BF01990193

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  12 in total

1.  Intestinal transport of 3H-digitoxin in vitro incompatible with simple diffusion.

Authors:  K H Damm; A Grosshauser; R R Erttmann
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1975       Impact factor: 3.000

2.  On the mechanism of action of probenecid on renal tubular secretion.

Authors:  I M WEINER; J A WASHINGTON; G H MUDGE
Journal:  Bull Johns Hopkins Hosp       Date:  1960-06

3.  Absorption of drugs from the rat small intestine.

Authors:  L S SCHANKER; D J TOCCO; B B BRODIE; C A HOGBEN
Journal:  J Pharmacol Exp Ther       Date:  1958-05       Impact factor: 4.030

4.  The effect of probenecid on the in vitro absorption of cardiac glycosides.

Authors:  K H Damm; C Woermann
Journal:  Eur J Pharmacol       Date:  1974-09       Impact factor: 4.432

5.  Probenecid and hepatic transport of 3-H-ouabain in rats.

Authors:  R Erttmann; K H Damm
Journal:  Arch Int Pharmacodyn Ther       Date:  1974-10

6.  [Studies on the active or passive enteral resorption of cardiac glycosides].

Authors:  P Mentz; H Witzleben; W Förster
Journal:  Arch Int Pharmacodyn Ther       Date:  1972-11

7.  Effects of phenolsulfonphthalein and probenecid on the uptake and utilization of citrate and -ketoglutarate by kidney, in vitro.

Authors:  A Pakarinen; L Runeberg
Journal:  Biochem Pharmacol       Date:  1969-10       Impact factor: 5.858

8.  Palmitate uptake and oxidation by kidney cortex slices. Effects of probenecid, p-aminohippurate and phenolsulfonphthalein.

Authors:  A Pakarinen
Journal:  Biochem Pharmacol       Date:  1970-10       Impact factor: 5.858

9.  Uptake and utilization of citrate and alpha-ketoglutarate by liver slices. Effects of phenolsulfonphthalein and probenecid.

Authors:  A Pakarinen
Journal:  Ann Med Exp Biol Fenn       Date:  1971

10.  The effect of inhibitors of renal transport on the small intestine.

Authors:  H J Binder; L A Katz; R P Spencer; H M Spiro
Journal:  J Clin Invest       Date:  1966-12       Impact factor: 14.808
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  1 in total

1.  Kinetics and inotropic action of probenecid in guinea-pig heart in vitro.

Authors:  R R Erttmann
Journal:  Experientia       Date:  1978-12-15
  1 in total

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