Literature DB >> 12769839

Early formation of mRNP: license for export or quality control?

Torben Heick Jensen1, Ken Dower, Domenico Libri, Michael Rosbash.   

Abstract

Eukaryotic mRNA is processed by enzymes and packaged with proteins within nuclei to generate functional messenger ribonucleoprotein (mRNP) particles. Processing and packaging factors can interact with mRNA cotranscriptionally to form an early mRNP. Erroneous mRNP formation leads to nuclear retention and degradation of the mRNA. It therefore appears that one function of cotranscriptional mRNP assembly is to discard aberrant mRNPs early in their biogenesis. Cotranscriptional mRNP assembly may also enable the transcription machinery to respond to improper mRNP formation.

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Substances：

Year:  2003        PMID： 12769839     DOI： 10.1016/s1097-2765(03)00191-6

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  49 in total

1.  Evidence that poly(A) binding protein has an evolutionarily conserved function in facilitating mRNA biogenesis and export.

Authors:  Julia A Chekanova; Dmitry A Belostotsky
Journal:  RNA       Date:  2003-12       Impact factor: 4.942

Review 2.  Nucleocytoplasmic transport: integrating mRNA production and turnover with export through the nuclear pore.

Authors:  Christian Dimaano; Katharine S Ullman
Journal:  Mol Cell Biol       Date:  2004-04       Impact factor: 4.272

3.  STABILIZED1, a stress-upregulated nuclear protein, is required for pre-mRNA splicing, mRNA turnover, and stress tolerance in Arabidopsis.

Authors:  Byeong-ha Lee; Avnish Kapoor; Jianhua Zhu; Jian-Kang Zhu
Journal:  Plant Cell       Date:  2006-06-02       Impact factor: 11.277

4.  Analysis of the Xist RNA isoforms suggests two distinctly different forms of regulation.

Authors:  Mingchao Ma; William M Strauss
Journal:  Mamm Genome       Date:  2005-06       Impact factor: 2.957

5.  Hsp27 enhances recovery of splicing as well as rephosphorylation of SRp38 after heat shock.

Authors:  Laura Marin-Vinader; Chanseok Shin; Carla Onnekink; James L Manley; Nicolette H Lubsen
Journal:  Mol Biol Cell       Date:  2005-12-07       Impact factor: 4.138

6.  Drosophila Paf1 modulates chromatin structure at actively transcribed genes.

Authors:  Karen Adelman; Wenxiang Wei; M Behfar Ardehali; Janis Werner; Bing Zhu; Danny Reinberg; John T Lis
Journal:  Mol Cell Biol       Date:  2006-01       Impact factor: 4.272

7.  Ubiquitin-associated domain of Mex67 synchronizes recruitment of the mRNA export machinery with transcription.

Authors:  Carole Gwizdek; Nahid Iglesias; Manuel S Rodriguez; Batool Ossareh-Nazari; Maria Hobeika; Gilles Divita; Françoise Stutz; Catherine Dargemont
Journal:  Proc Natl Acad Sci U S A       Date:  2006-10-20       Impact factor: 11.205

8.  Nuclear pre-mRNA decapping and 5' degradation in yeast require the Lsm2-8p complex.

Authors:  Joanna Kufel; Cecile Bousquet-Antonelli; Jean D Beggs; David Tollervey
Journal:  Mol Cell Biol       Date:  2004-11       Impact factor: 4.272

9.  The growing pre-mRNA recruits actin and chromatin-modifying factors to transcriptionally active genes.

Authors:  Mikael Sjölinder; Petra Björk; Emilia Söderberg; Nafiseh Sabri; Ann-Kristin Ostlund Farrants; Neus Visa
Journal:  Genes Dev       Date:  2005-08-15       Impact factor: 11.361

10.  The Evolutionarily-conserved Polyadenosine RNA Binding Protein, Nab2, Cooperates with Splicing Machinery to Regulate the Fate of pre-mRNA.

Authors:  Sharon Soucek; Yi Zeng; Deepti L Bellur; Megan Bergkessel; Kevin J Morris; Qiudong Deng; Duc Duong; Nicholas T Seyfried; Christine Guthrie; Jonathan P Staley; Milo B Fasken; Anita H Corbett
Journal:  Mol Cell Biol       Date:  2016-08-15       Impact factor: 4.272
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