Literature DB >> 1276818

High-dose corticosteroids in severe acute asthma.

M G Britton, J V Collins, D Brown, N P Fairhurst, R G Lambert.   

Abstract

Twenty-six patients admitted to hospital for treatment of severe exacerbations of asthma unresponsive to bronchodilators were assigned to high-, medium-, or low-dose corticosteroid treatment regimens. The rates of recovery were assessed by changes in pulse rate, peak expiratory flow rate, and spirometric measurements and were not related to the dose of corticosteroids given. Very high systemic doses of corticosteroids do not offer significant advantages in treating severe exacerbations of asthma.

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Year:  1976        PMID: 1276818      PMCID: PMC1687810          DOI: 10.1136/bmj.2.6027.73

Source DB:  PubMed          Journal:  Br Med J        ISSN: 0007-1447


  2 in total

1.  Intravenous corticosteroids in treatment of acute bronchial asthma.

Authors:  J V Collins; T J Clark; P W Harris; J Townsend
Journal:  Lancet       Date:  1970-11-21       Impact factor: 79.321

2.  The use of corticosteroids in the treatment of acute asthma.

Authors:  J V Collins; T J Clark; D Brown; J Townsend
Journal:  Q J Med       Date:  1975-04
  2 in total
  11 in total

1.  Effects of corticosteroids in acute severe asthma.

Authors:  N C Barnes
Journal:  Thorax       Date:  1992-08       Impact factor: 9.139

2.  Treatment of acute asthma: effect of intravenous corticosteroids and beta 2-adrenergic agonists.

Authors:  A Arnaud; D Vervloet; P Dugue; J Orehek; J Charpin
Journal:  Lung       Date:  1979       Impact factor: 2.584

3.  "Acute" asthma in adults.

Authors:  D Bellamy; J V Collins
Journal:  Thorax       Date:  1979-02       Impact factor: 9.139

Review 4.  Status asthmaticus in adults.

Authors:  H Don
Journal:  Clin Rev Allergy       Date:  1985-02

Review 5.  The management of acute severe asthma.

Authors:  M E Tatham; A R Gellert
Journal:  Postgrad Med J       Date:  1985-07       Impact factor: 2.401

Review 6.  Guidelines for the emergency management of asthma in adults. CAEP/CTS Asthma Advisory Committee. Canadian Association of Emergency Physicians and the Canadian Thoracic Society.

Authors:  R C Beveridge; A F Grunfeld; R V Hodder; P R Verbeek
Journal:  CMAJ       Date:  1996-07-01       Impact factor: 8.262

7.  Randomised pragmatic comparison of UK and US treatment of acute asthma presenting to hospital.

Authors:  N J Innes; J A Stocking; T J Daynes; B D W Harrison
Journal:  Thorax       Date:  2002-12       Impact factor: 9.139

8.  Pharmacokinetics of dexamethasone in premature neonates.

Authors:  R A Lugo; M C Nahata; J A Menke; R E McClead
Journal:  Eur J Clin Pharmacol       Date:  1996       Impact factor: 2.953

9.  Continuous nebulised salbutamol and oral once a day prednisolone in status asthmaticus.

Authors:  M Singh; L Kumar
Journal:  Arch Dis Child       Date:  1993-10       Impact factor: 3.791

10.  Intravenously given methylprednisolone in refractory asthma.

Authors:  H A Krouse; S M Santiago; W B Klaustermeyer
Journal:  West J Med       Date:  1980-02
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