Literature DB >> 1276668

Cancer prognosis predicted by preoperative lymphocyte responsiveness in vitro.

S M Watkins.   

Abstract

The prognosis in cancer patients was studied in relation to their preoperative cell-mediated immune status. Thirty patients with various types of operable cancer were studied. Transformation of the lymphocytes in response to phytohaemagglutinin (PHA) in vitro was measured preoperatively. All the patients were followed up for 3 years. Those with normal preoperative lymphocyte responsiveness had a far better prognosis than those in whom this test was subnormal.

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Year:  1976        PMID: 1276668     DOI: 10.1002/bjs.1800630605

Source DB:  PubMed          Journal:  Br J Surg        ISSN: 0007-1323            Impact factor:   6.939


  6 in total

1.  Suppression of in vitro peripheral blood lymphocyte mitogenesis by cytotoxic drugs commonly used in the treatment of breast cancer: a comparative study.

Authors:  M Gereis; A P Burford-Mason; S M Watkins
Journal:  Agents Actions       Date:  1987-12

2.  Nutritional status and the nonspecific cellular and humoral immune response in esophageal carcinoma.

Authors:  A A Haffejee; I B Angorn
Journal:  Ann Surg       Date:  1979-04       Impact factor: 12.969

3.  Evaluation of lymphocyte immunity in breast cancer patients.

Authors:  J F Head; R L Elliott; J L McCoy
Journal:  Breast Cancer Res Treat       Date:  1993       Impact factor: 4.872

4.  Phytohaemagglutinin responsiveness of peripheral lymphocytes and survival in patients with primary breast cancer.

Authors:  A Burford-Mason; G M Gyte; S M Watkins
Journal:  Breast Cancer Res Treat       Date:  1989-07       Impact factor: 4.872

5.  Long-term (5-11 years) follow-up of general immune competence in breast cancer. I. Pre-treatment levels with reference to micrometastasis.

Authors:  H S Shukla; L E Hughes; R H Whitehead; R G Newcombe
Journal:  Cancer Immunol Immunother       Date:  1986       Impact factor: 6.968

6.  Comparison of estrogen and progesterone receptor status to lymphocyte immunity against tumor antigens in breast cancer patients.

Authors:  R L Elliott; J F Head; J L McCoy
Journal:  Breast Cancer Res Treat       Date:  1994       Impact factor: 4.872

  6 in total

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