Literature DB >> 12762803

Brominated polyacetylenes from the Philippines sponge Diplastrella sp.

Melissa L Lerch1, Mary Kay Harper, D John Faulkner.   

Abstract

Five novel brominated polyacetylenic diols, diplynes A-E (2-6), and three sulfated analogues, diplyne A 1-sulfate (7), diplyne C 1-sulfate (8), and 2-deoxydiplyne D sulfate (9), were isolated from the Philippines sponge Diplastrella sp. by employing bioassay-guided fractionation using the HIV-1 integrase inhibition assay. The novel metabolites were characterized by interpretation of spectroscopic data.

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Year:  2003        PMID： 12762803     DOI： 10.1021/np020544+

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  7 in total

1.  Identification of sulfation sites of metabolites and prediction of the compounds' biological effects.

Authors:  Lin Yi; Joe Dratter; Chao Wang; Jon A Tunge; Heather Desaire
Journal:  Anal Bioanal Chem       Date:  2006-05-25       Impact factor: 4.142

2.  Faulknerynes A-C from a Bahamian sponge Diplastrella sp.: stereoassignment by critical application of two exciton coupled CD methods.

Authors:  Jaeyoung Ko; Brandon I Morinaka; Tadeusz F Molinski
Journal:  J Org Chem       Date:  2011-01-10       Impact factor: 4.354

Review 3.  Biosynthesis and function of polyacetylenes and allied natural products.

Authors:  Robert E Minto; Brenda J Blacklock
Journal:  Prog Lipid Res       Date:  2008-03-13       Impact factor: 16.195

4.  Identification of novel acetylenic alcohols and a new dihydrothiopyranone from the tropical sponge Reniochalina sp.

Authors:  Hyi-Seung Lee; Ji Hye Lee; Hoshik Won; Song-Kyu Park; Hwan Mook Kim; Hee Jae Shin; Heung Sik Park; Chung J Sim; Hye-Kyeong Kim
Journal:  Lipids       Date:  2008-10-22       Impact factor: 1.880

5.  A facile copper(I)-catalyzed homocoupling of terminal alkynes to 1,3-diynes with diaziridinone under mild conditions.

Authors:  Yingguang Zhu; Yian Shi
Journal:  Org Biomol Chem       Date:  2013-11-21       Impact factor: 3.876

6.  Highly selective cross-coupling reactions of 1,1-dibromoethylenes with alkynylaluminums for the synthesis of aryl substituted conjugated enediynes and unsymmetrical 1,3-diynes.

Authors:  Kun Wu; Chuan Wu; Xiao-Ying Jia; Lin Zhou; Qing-Han Li
Journal:  RSC Adv       Date:  2022-05-03       Impact factor: 4.036

7.  Placotylene A, an inhibitor of the receptor activator of nuclear factor-κB ligand-induced osteoclast differentiation, from a Korean sponge Placospongia sp.

Authors:  Hiyoung Kim; Kwang-Jin Kim; Jeong-Tae Yeon; Seong Hwan Kim; Dong Hwan Won; Hyukjae Choi; Sang-Jip Nam; Young-Jin Son; Heonjoong Kang
Journal:  Mar Drugs       Date:  2014-04-03       Impact factor: 5.118
  7 in total

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