Literature DB >> 12760882

Stability and antibacterial activity of cefepime during continuous infusion.

Pål F Sprauten1, Paul M Beringer, Stan G Louie, Timothy W Synold, Mark A Gill.   

Abstract

The stability of cefepime during simulated continuous infusion was determined with a motorized portable infusion pump worn over a period of 24 to 36 h. Susceptibility testing on cefepime solutions over time indicates that the degradation products do not exhibit antibacterial activity. Cefepime stability at 24 h following continuous infusion was 94.3% +/- 1.0%, which supports the use of continuous infusion.

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Year:  2003        PMID： 12760882      PMCID： PMC155835          DOI： 10.1128/AAC.47.6.1991-1994.2003

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  15 in total

1.  Stability and degradation pattern of cefpirome (HR 810) in aqueous solution.

Authors:  T Sugioka; T Asano; Y Chikaraishi; E Suzuki; A Sano; T Kuriki; M Shirotsuka; K Saito
Journal:  Chem Pharm Bull (Tokyo)       Date:  1990-07       Impact factor: 1.645

2.  A kinetic oxymoron: concentration-dependent first-order rate constants for hydrolysis of ceftazidime.

Authors:  J O Fubara; R E Notari
Journal:  J Pharm Sci       Date:  1998-01       Impact factor: 3.534

3.  High-performance liquid chromatographic assay for cefepime in serum.

Authors:  H Elkhaïli; L Linger; H Monteil; F Jehl
Journal:  J Chromatogr B Biomed Sci Appl       Date:  1997-03-07

4.  Pharmacokinetics of cefepime in cystic fibrosis patients.

Authors:  C E Huls; R A Prince; D K Seilheimer; J A Bosso
Journal:  Antimicrob Agents Chemother       Date:  1993-07       Impact factor: 5.191

5.  Stability of cefepime in peritoneal dialysis solution.

Authors:  J C Williamson; D F Volles; P L Lynch; P D Rogers; D M Haverstick
Journal:  Ann Pharmacother       Date:  1999-09       Impact factor: 3.154

6.  Clinical efficacy and pharmacoeconomics of a continuous-infusion piperacillin-tazobactam program in a large community teaching hospital.

Authors:  Edward M Grant; Joseph L Kuti; David P Nicolau; Charles Nightingale; Richard Quintiliani
Journal:  Pharmacotherapy       Date:  2002-04       Impact factor: 4.705

7.  Pharmacokinetics of ceftazidime in adult cystic fibrosis patients during continuous infusion and ambulatory treatment at home.

Authors:  A A Vinks; D J Touw; H G Heijerman; M Danhof; G P de Leede; W Bakker
Journal:  Ther Drug Monit       Date:  1994-08       Impact factor: 3.681

8.  Cefepime. Pharmacokinetics and clinical response in patients with cystic fibrosis.

Authors:  A G Arguedas; H R Stutman; M Zaleska; C A Knupp; M I Marks; E Nussbaum
Journal:  Am J Dis Child       Date:  1992-07

9.  Cefepime pharmacokinetics in cystic fibrosis.

Authors:  B A Hamelin; N Moore; C A Knupp; M Ruel; F Vallée; M LeBel
Journal:  Pharmacotherapy       Date:  1993 Sep-Oct       Impact factor: 4.705

Review 10.  Beta-lactam antibiotics: is continuous infusion the preferred method of administration?

Authors:  T G Vondracek
Journal:  Ann Pharmacother       Date:  1995-04       Impact factor: 3.154
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  4 in total

1.  Pharmacodynamics of cefepime alone and in combination with various antimicrobials against methicillin-resistant Staphylococcus aureus in an in vitro pharmacodynamic infection model.

Authors:  Vanthida Huang; Michael J Rybak
Journal:  Antimicrob Agents Chemother       Date:  2005-01       Impact factor: 5.191

Review 2.  Systematic review of stability data pertaining to selected antibiotics used for extended infusions in outpatient parenteral antimicrobial therapy (OPAT) at standard room temperature and in warmer climates.

Authors:  Stephen John Perks; Cassie Lanskey; Niechole Robinson; Tilley Pain; Richard Franklin
Journal:  Eur J Hosp Pharm       Date:  2019-06-20

3.  Preparation and Characterization of New Liposomes. Bactericidal Activity of Cefepime Encapsulated into Cationic Liposomes.

Authors:  Maria Luisa Moyá; Manuel López-López; José Antonio Lebrón; Francisco José Ostos; David Pérez; Vanesa Camacho; Irene Beck; Vicente Merino-Bohórquez; Manuel Camean; Nuria Madinabeitia; Pilar López-Cornejo
Journal:  Pharmaceutics       Date:  2019-02-06       Impact factor: 6.321

4.  Chemical Stability of Ceftolozane/Tazobactam in Polyvinylchloride Bags and Elastomeric Pumps.

Authors:  Joseph Terracciano; Elizabeth G Rhee; Jacqueline Walsh
Journal:  Curr Ther Res Clin Exp       Date:  2017-03-06
  4 in total

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