| Literature DB >> 12760855 |
Marja Pihlajamäki1, Jari Jalava, Pentti Huovinen, Pirkko Kotilainen.
Abstract
The resistance patterns and macrolide resistance mechanisms of 910 Finnish invasive pneumococci isolated during 1999 and 2000 were studied. Macrolide resistance was detected in 6.9% of isolates. Penicillin resistance was detected in 1.5% of isolates, and penicillin intermediate resistance was detected in 4.0% of isolates. Active macrolide efflux, mediated by the mef(A) gene, was the most common macrolide resistance mechanism. Four macrolide-resistant isolates had mutations in rRNA or ribosomal protein L22.Entities:
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Year: 2003 PMID: 12760855 PMCID: PMC155848 DOI: 10.1128/AAC.47.6.1832-1835.2003
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191