Literature DB >> 12757612

Innate self recognition by an invariant, rearranged T-cell receptor and its immune consequences.

Aleksandar K Stanic1, Jang-June Park, Sebastian Joyce.   

Abstract

This review attempts to illuminate the glycolipid antigen presentation properties of CD1d, how CD1d controls the function of natural T (iNKT) cells and how CD1d and iNKT cells interact to jump-start the immune system. It is postulated that the CD1d-iNKT cell system functions as a sensor, sensing alterations in cellular lipid content by virtue of its affinity for such ligands. The presentation of a neo-self glycolipid, presumably by infectious assault of antigen-presenting cells, activates iNKT cells, which promptly release pro-inflammatory and anti-inflammatory cytokines and jump-start the immune system.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 12757612      PMCID： PMC1782955          DOI： 10.1046/j.1365-2567.2003.01657.x

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  156 in total

1.  NKT cells provide help for dendritic cell-dependent priming of MHC class I-restricted CD8+ T cells in vivo.

Authors:  Detlef Stober; Ieva Jomantaite; Reinhold Schirmbeck; Jörg Reimann
Journal:  J Immunol       Date:  2003-03-01       Impact factor: 5.422

Review 2.  The NK cell receptor repertoire: formation, adaptation and exploitation.

Authors:  Werner Held; Jérôme D Coudert; Jacques Zimmer
Journal:  Curr Opin Immunol       Date:  2003-04       Impact factor: 7.486

Review 3.  The regulatory role of Valpha14 NKT cells in innate and acquired immune response.

Authors:  Masaru Taniguchi; Michishige Harada; Satoshi Kojo; Toshinori Nakayama; Hiroshi Wakao
Journal:  Annu Rev Immunol       Date:  2001-12-19       Impact factor: 28.527

4.  NK1.1+ CD4+ T cells lose NK1.1 expression upon in vitro activation.

Authors:  H Chen; H Huang; W E Paul
Journal:  J Immunol       Date:  1997-06-01       Impact factor: 5.422

5.  Inability of CD8 alpha' polypeptides to associate with p56lck correlates with impaired function in vitro and lack of expression in vivo.

Authors:  R Zamoyska; P Derham; S D Gorman; P von Hoegen; J B Bolen; A Veillette; J R Parnes
Journal:  Nature       Date:  1989-11-16       Impact factor: 49.962

Review 6.  Phospholipid biosynthesis in yeast.

Authors:  G M Carman; S A Henry
Journal:  Annu Rev Biochem       Date:  1989       Impact factor: 23.643

7.  Crystal structure of mouse CD1: An MHC-like fold with a large hydrophobic binding groove.

Authors:  Z Zeng; A R Castaño; B W Segelke; E A Stura; P A Peterson; I A Wilson
Journal:  Science       Date:  1997-07-18       Impact factor: 47.728

8.  The contribution of NKT cells, NK cells, and other gamma-chain-dependent non-T non-B cells to IL-12-mediated rejection of tumors.

Authors:  Se-Ho Park; Tim Kyin; Albert Bendelac; Claude Carnaud
Journal:  J Immunol       Date:  2003-02-01       Impact factor: 5.422

9.  CD1d-restricted natural killer T cells are potent targets for human immunodeficiency virus infection.

Authors:  Richardson Fleuridor; Brian Wilson; Runhua Hou; Alan Landay; Harold Kessler; Lena Al-Harthi
Journal:  Immunology       Date:  2003-01       Impact factor: 7.397

10.  CD1d-expressing dendritic cells but not thymic epithelial cells can mediate negative selection of NKT cells.

Authors:  Taehoon Chun; Michael J Page; Laurent Gapin; Jennifer L Matsuda; Honglin Xu; Hanh Nguyen; Hyung-Sik Kang; Aleksandar K Stanic; Sebastian Joyce; Walter A Koltun; Michael J Chorney; Mitchell Kronenberg; Chyung-Ru Wang
Journal:  J Exp Med       Date:  2003-04-07       Impact factor: 14.307
View more
  3 in total

1.  Commitment toward the natural T (iNKT) cell lineage occurs at the CD4+8+ stage of thymic ontogeny.

Authors:  Jelena S Bezbradica; Timothy Hill; Aleksandar K Stanic; Luc Van Kaer; Sebastian Joyce
Journal:  Proc Natl Acad Sci U S A       Date:  2005-03-25       Impact factor: 11.205

2.  Alpha versus beta: are we on the way to resolve the mystery as to which is the endogenous ligand for natural killer T cells?

Authors:  Y Ilan
Journal:  Clin Exp Immunol       Date:  2009-09-30       Impact factor: 4.330

3.  Beta-glycoglycosphingolipid-induced alterations of the STAT signaling pathways are dependent on CD1d and the lipid raft protein flotillin-2.

Authors:  Gadi Lalazar; Ami Ben Ya'acov; Dan M Livovsky; Madi El Haj; Orit Pappo; Sarah Preston; Lidya Zolotarov; Yaron Ilan
Journal:  Am J Pathol       Date:  2009-02-26       Impact factor: 4.307
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.