OBJECTIVES: To examine the reporting accuracy of collateral sources (knowledgeable informants) regarding very mild and mild dementia of the Alzheimer type (DAT) and to identify characteristics associated with collateral source accuracy. DESIGN: Secondary data analysis of initial visits of individuals enrolled in a longitudinal study of healthy aging and Alzheimer disease. SETTING: Urban Alzheimer disease research center. PARTICIPANTS: Pairs of 515 individuals with very mild (n = 203) or mild (n = 312) DAT and their collateral sources. MEASUREMENTS: Collateral sources were asked separately during a semistructured interview by experienced clinicians to report current ability of the individual with DAT in memory, orientation, and judgment and problem solving. The clinical performance of the individuals with DAT in these domains was compared with these predictions. RESULTS: Collateral sources were consistently and significantly accurate in reporting the cognitive capabilities of individuals with very mild and mild DAT. Although all types of collateral sources performed significantly better than chance, individual variables that correlated with collateral source accuracy included spousal relationship; living with the individual with DAT; frequent exposure to the individual; and age, education level, sex and dementia severity of the individual with DAT. CONCLUSION: Collateral sources are accurate in reporting the cognitive capabilities of individuals with DAT, even in the very mild stage of dementia.
OBJECTIVES: To examine the reporting accuracy of collateral sources (knowledgeable informants) regarding very mild and mild dementia of the Alzheimer type (DAT) and to identify characteristics associated with collateral source accuracy. DESIGN: Secondary data analysis of initial visits of individuals enrolled in a longitudinal study of healthy aging and Alzheimer disease. SETTING: Urban Alzheimer disease research center. PARTICIPANTS: Pairs of 515 individuals with very mild (n = 203) or mild (n = 312) DAT and their collateral sources. MEASUREMENTS: Collateral sources were asked separately during a semistructured interview by experienced clinicians to report current ability of the individual with DAT in memory, orientation, and judgment and problem solving. The clinical performance of the individuals with DAT in these domains was compared with these predictions. RESULTS: Collateral sources were consistently and significantly accurate in reporting the cognitive capabilities of individuals with very mild and mild DAT. Although all types of collateral sources performed significantly better than chance, individual variables that correlated with collateral source accuracy included spousal relationship; living with the individual with DAT; frequent exposure to the individual; and age, education level, sex and dementia severity of the individual with DAT. CONCLUSION: Collateral sources are accurate in reporting the cognitive capabilities of individuals with DAT, even in the very mild stage of dementia.
Authors: James E Galvin; Thomas M Meuser; Mary A Coats; Donald A Bakal; John C Morris Journal: Alzheimer Dis Assoc Disord Date: 2009 Jan-Mar Impact factor: 2.703
Authors: Jianzhao Shen; Sujuan Gao; Frederick W Unverzagt; Adesola Ogunniyi; Olusegun Baiyewu; Oye Gureje; Hugh C Hendrie; Kathleen S Hall Journal: Int J Geriatr Psychiatry Date: 2006-07 Impact factor: 3.485
Authors: Joel H Kramer; Adam Nelson; Julene K Johnson; Kristine Yaffe; Shenly Glenn; Howard J Rosen; Bruce L Miller Journal: Dement Geriatr Cogn Disord Date: 2006-08-23 Impact factor: 2.959
Authors: Sarah H Stout; Ganesh M Babulal; Chunyu Ma; David B Carr; Denise M Head; Elizabeth A Grant; Monique M Williams; David M Holtzman; Anne M Fagan; John C Morris; Catherine M Roe Journal: Alzheimers Dement Date: 2018-01-10 Impact factor: 21.566