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Literature DB >> 12756320

The effect of nonsense codons on splicing: a genomic analysis.

Xiang Zhang, James Lee, Lawrence A Chasin.

Abstract

The phenomenon of nonsense-associated altered splicing raises the possibility that the recognition of in-frame nonsense codons is used generally for exon identification during pre-mRNA splicing. However, nonsense codon frequencies in pseudo exons and in regions flanking 5' splice sites are no greater than that expected by chance, arguing against the widespread use of this strategy as a means of rejecting potential splice sites.

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Year: 2003 PMID： 12756320 PMCID： PMC1370429 DOI： 10.1261/rna.5060403

Source DB: PubMed Journal: RNA ISSN： 1355-8382 Impact factor: 4.942

13 in total

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Journal: Nature Date: 2001-02-15 Impact factor: 49.962

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Journal: Mol Cell Biol Date: 2000-09 Impact factor: 4.272

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9 in total

Review 1. Regulation of splicing: the importance of being translatable.

Authors: Elana Miriami; Ruth Sperling; Joseph Sperling; Uzi Motro
Journal: RNA Date: 2004-01 Impact factor: 4.942

Review 2. Latent splice sites and stop codons revisited.

Authors: Xiang H-F Zhang; Lawrence A Chasin
Journal: RNA Date: 2004-01 Impact factor: 4.942

Review 3. Tissue Elasticity Bridges Cancer Stem Cells to the Tumor Microenvironment Through microRNAs: Implications for a "Watch-and-Wait" Approach to Cancer.

Authors: Shengwen Calvin Li; Long T Vu; Jane Jianying Luo; Jiang F Zhong; Zhongjun Li; Brent A Dethlefs; William G Loudon; Mustafa H Kabeer
Journal: Curr Stem Cell Res Ther Date: 2017 Impact factor: 3.828

9. Identification of donor splice sites using support vector machine: a computational approach based on positional, compositional and dependency features.

Authors: Prabina Kumar Meher; Tanmaya Kumar Sahu; A R Rao; S D Wahi
Journal: Algorithms Mol Biol Date: 2016-06-01 Impact factor: 1.405