Marc J Dubois1, Daniel De Backer2, Jacques Creteur1, Sami Anane1, Jean-Louis Vincent1. 1. Department of Intensive Care Medicine, Erasme Hospital, Route de Lennik 808, 1070, Brussels, Belgium. 2. Department of Intensive Care Medicine, Erasme Hospital, Route de Lennik 808, 1070, Brussels, Belgium. ddebacke@ulb.ac.be.
Abstract
OBJECTIVE: To assess the sublingual microcirculation in a patient during vasopressin administration for a distributive shock after cardiopulmonary bypass. DESIGN AND SETTING: Case-report in the Department of Intensive Care of a university hospital. PATIENT: A 53 year-old man developed severe distributive shock after cardiac transplant, requiring massive doses of vasopressor agents. METHODS: Vasopressin administered twice at a dose of 0.02 U/min increased mean blood pressure and allowed partial weaning of other vasopressor drugs. Microcirculatory alterations were assessed by orthogonal polarization spectral technique: 50% and 60% of capillaries were perfused at baseline, and these proportions did not worsen when vasopressin was administered. CONCLUSIONS: Despite its strong vasopressor effects vasopressin infusion did not worsen microcirculatory alterations in this patient with distributive shock following cardiac surgery.
OBJECTIVE: To assess the sublingual microcirculation in a patient during vasopressin administration for a distributive shock after cardiopulmonary bypass. DESIGN AND SETTING: Case-report in the Department of Intensive Care of a university hospital. PATIENT: A 53 year-old man developed severe distributive shock after cardiac transplant, requiring massive doses of vasopressor agents. METHODS:Vasopressin administered twice at a dose of 0.02 U/min increased mean blood pressure and allowed partial weaning of other vasopressor drugs. Microcirculatory alterations were assessed by orthogonal polarization spectral technique: 50% and 60% of capillaries were perfused at baseline, and these proportions did not worsen when vasopressin was administered. CONCLUSIONS: Despite its strong vasopressor effects vasopressin infusion did not worsen microcirculatory alterations in this patient with distributive shock following cardiac surgery.
Authors: C Varga; I Pávó; D Lamarque; Z Szepes; J Kiss; G Karácsony; F A László; F László Journal: Eur J Pharmacol Date: 1998-07-10 Impact factor: 4.432
Authors: Andrea Morelli; Abele Donati; Christian Ertmer; Sebastian Rehberg; Alessandra Orecchioni; Alessandro Di Russo; Paolo Pelaia; Paolo Pietropaoli; Martin Westphal Journal: Intensive Care Med Date: 2011-02-19 Impact factor: 17.440
Authors: Djillali Annane; Lamia Ouanes-Besbes; Daniel de Backer; Bin DU; Anthony C Gordon; Glenn Hernández; Keith M Olsen; Tiffany M Osborn; Sandra Peake; James A Russell; Sergio Zanotti Cavazzoni Journal: Intensive Care Med Date: 2018-06-04 Impact factor: 17.440