| Literature DB >> 12736741 |
Yolanda Blanco1, Jordi Yagüe, Francesc Graus, Albert Saiz.
Abstract
Nitric oxide (NO) is a nonspecific inflammatory mediator that has been involved in the pathogenesis of multiple sclerosis (MS). The influence of the promoter polymorphism of inducible NO synthase gene ( NOS2A) on susceptibility and outcome was studied in 140 MS Spanish patients and 147 healthy controls matched for sex, age, and ethnicity. No association was found between MS susceptibility, course or outcome of the disease, and NOS2A polymorphisms.Entities:
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Year: 2003 PMID： 12736741 DOI： 10.1007/s00415-003-1047-7
Source DB: PubMed Journal: J Neurol ISSN： 0340-5354 Impact factor: 4.849