Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Nitric oxide and multiple sclerosis.

Literature DB >> 15865889

Nitric oxide and multiple sclerosis.

Juan Manuel Encinas¹, Louis Manganas, Grigori Enikolopov.

Abstract

Nitric oxide (NO) is a free radical signaling molecule with remarkably complex biochemistry. Its involvement in multiple sclerosis (MS) had been postulated soon after the discovery of the critical role NO plays in inflammation. However, the extent of NO's contribution to MS is not yet understood, party due to the often opposing roles that NO can play in cellular processes. This review briefly covers new developments in the area of NO that may be relevant to MS. It also describes recent progress in understanding the role of NO in MS, new potential targets of the action of NO in the cell, and prospects for NO-based therapies.

Entities: Chemical Disease

Mesh：

Substances：

Year: 2005 PMID： 15865889 DOI： 10.1007/s11910-005-0051-y

Source DB: PubMed Journal: Curr Neurol Neurosci Rep ISSN： 1528-4042 Impact factor: 5.081

60 in total

1. Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity.

Authors: Dongdong Yao; Zezong Gu; Tomohiro Nakamura; Zhong-Qing Shi; Yuliang Ma; Benjamin Gaston; Lisa A Palmer; Edward M Rockenstein; Zhuohua Zhang; Eliezer Masliah; Takashi Uehara; Stuart A Lipton
Journal: Proc Natl Acad Sci U S A Date: 2004-07-13 Impact factor: 11.205

2. Cellular targets and mechanisms of nitros(yl)ation: an insight into their nature and kinetics in vivo.

Authors: Nathan S Bryan; Tienush Rassaf; Ronald E Maloney; Cynthia M Rodriguez; Fumito Saijo; Juan R Rodriguez; Martin Feelisch
Journal: Proc Natl Acad Sci U S A Date: 2004-03-10 Impact factor: 11.205

3. Nitric oxide synthase is present in the cerebrospinal fluid of patients with active multiple sclerosis and is associated with increases in cerebrospinal fluid protein nitrotyrosine and S-nitrosothiols and with changes in glutathione levels.

Authors: Vittorio Calabrese; Giovanni Scapagnini; Agrippino Ravagna; Rita Bella; Roberta Foresti; Timothy E Bates; Anna-Maria Giuffrida Stella; Giovanni Pennisi
Journal: J Neurosci Res Date: 2002-11-15 Impact factor: 4.164

Review 4. The role of nitric oxide in multiple sclerosis.

Authors: J F Parkinson; B Mitrovic; J E Merrill
Journal: J Mol Med (Berl) Date: 1997-03 Impact factor: 4.599

Review 5. Inducible nitric oxide synthase: what difference does it make?

Authors: C Nathan
Journal: J Clin Invest Date: 1997-11-15 Impact factor: 14.808

Review 6. Protein S-nitrosylation: purview and parameters.

Authors: Douglas T Hess; Akio Matsumoto; Sung-Oog Kim; Harvey E Marshall; Jonathan S Stamler
Journal: Nat Rev Mol Cell Biol Date: 2005-02 Impact factor: 94.444

7. Nitric oxide from inflammatory-activated glia synergizes with hypoxia to induce neuronal death.

Authors: Palwinder Mander; Vilma Borutaite; Salvador Moncada; Guy C Brown
Journal: J Neurosci Res Date: 2005 Jan 1-15 Impact factor: 4.164

8. Crosstalk between nitric oxide and zinc pathways to neuronal cell death involving mitochondrial dysfunction and p38-activated K+ channels.

Authors: Ella Bossy-Wetzel; Maria V Talantova; Wilson D Lee; Marion N Schölzke; Anne Harrop; Emily Mathews; Thomas Götz; Jiahuai Han; Mark H Ellisman; Guy A Perkins; Stuart A Lipton
Journal: Neuron Date: 2004-02-05 Impact factor: 17.173

9. Peroxynitrite-induced oligodendrocyte toxicity is not dependent on poly(ADP-ribose) polymerase activation.

Authors: Gwen S Scott; Laszlo Virág; Csaba Szabó; D Craig Hooper
Journal: Glia Date: 2003-01-15 Impact factor: 7.452

Review 10. Demyelination: the role of reactive oxygen and nitrogen species.

Authors: K J Smith; R Kapoor; P A Felts
Journal: Brain Pathol Date: 1999-01 Impact factor: 6.508

13 in total

1. Immune-Inflammatory and Oxidative and Nitrosative Stress Biomarkers of Depression Symptoms in Subjects with Multiple Sclerosis: Increased Peripheral Inflammation but Less Acute Neuroinflammation.

Authors: Ana Paula Kallaur; Josiane Lopes; Sayonara Rangel Oliveira; Andrea Name Colado Simão; Edna Maria Vissoci Reiche; Elaine Regina Delicato de Almeida; Helena Kaminami Morimoto; Wildea Lice Carvalho Jennings de Pereira; Daniele Frizon Alfieri; Sueli Donizete Borelli; Domacio Ramon Kaimen-Maciel; Michael Maes
Journal: Mol Neurobiol Date: 2015-09-24 Impact factor: 5.590

2. Myelin basic protein induces inflammatory mediators from primary human endothelial cells and blood-brain barrier disruption: implications for the pathogenesis of multiple sclerosis.

Authors: T G D'Aversa; E A Eugenin; L Lopez; J W Berman
Journal: Neuropathol Appl Neurobiol Date: 2013-04 Impact factor: 8.090

3. Characterizing brain oxygen metabolism in patients with multiple sclerosis with T2-relaxation-under-spin-tagging MRI.

Authors: Yulin Ge; Zhongwei Zhang; Hanzhang Lu; Lin Tang; Hina Jaggi; Joseph Herbert; James S Babb; Henry Rusinek; Robert I Grossman
Journal: J Cereb Blood Flow Metab Date: 2012-01-18 Impact factor: 6.200

4. Brain oxygen extraction fraction mapping in patients with multiple sclerosis.

Authors: Junghun Cho; Thanh D Nguyen; Weiyuan Huang; Elizabeth M Sweeney; Xianfu Luo; Ilhami Kovanlikaya; Shun Zhang; Kelly M Gillen; Pascal Spincemaille; Ajay Gupta; Susan A Gauthier; Yi Wang
Journal: J Cereb Blood Flow Metab Date: 2021-09-24 Impact factor: 6.960

5. Absence of the cellular prion protein exacerbates and prolongs neuroinflammation in experimental autoimmune encephalomyelitis.

Authors: Shigeki Tsutsui; Jennifer N Hahn; Trina A Johnson; Zenobia Ali; Frank R Jirik
Journal: Am J Pathol Date: 2008-10 Impact factor: 4.307