| Literature DB >> 12730187 |
Lara G S De Bie1, Martine Roovers, Yamina Oudjama, Ruddy Wattiez, Catherine Tricot, Victor Stalon, Louis Droogmans, Janusz M Bujnicki.
Abstract
We cloned, expressed, and purified the Escherichia coli YggH protein and show that it catalyzes the S-adenosyl-L-methionine-dependent formation of N(7)-methylguanosine at position 46 (m(7)G46) in tRNA. Additionally, we generated an E. coli strain with a disrupted yggH gene and show that the mutant strain lacks tRNA (m(7)G46) methyltransferase activity.Entities:
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Year: 2003 PMID: 12730187 PMCID: PMC154064 DOI: 10.1128/JB.185.10.3238-3243.2003
Source DB: PubMed Journal: J Bacteriol ISSN: 0021-9193 Impact factor: 3.490