Literature DB >> 12729638

Identification of 2-aminobenzimidazole dimers as antibacterial agents.

Punit P Seth1, Elizabeth A Jefferson, Lisa M Risen, Stephen A Osgood.   

Abstract

The preparation and evaluation of 2-aminobenzimidazole dimers as antibacterial agents is described. Biological screening of the dimers indicated that compounds with multiple chloro substituents possessed optimal antibacterial activity.

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Year:  2003        PMID： 12729638     DOI： 10.1016/s0960-894x(03)00245-2

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  4 in total

1.  Parallel Solid-Phase Synthesis of disubstituted 3-(1H-benzo[d]imidazol-2-yl)imidazolidine-2,4-diones and 3-(1H-benzo[d]imidazol-2-yl)-2-thioxoimidazolidin-4-ones.

Authors:  Sureshbabu Dadiboyena; Adel Nefzi
Journal:  Tetrahedron Lett       Date:  2011-12-28       Impact factor: 2.415

2.  Diversity oriented synthesis and IKK inhibition of aminobenzimidazole tethered quinazoline-2,4-diones, thioxoquinazolin-4-ones, benzodiazepine-2,3,5-triones, isoxazoles and isoxazolines.

Authors:  Sureshbabu Dadiboyena; Aïcha Arfaoui; Hassen Amri; F Javier Piedrafita; Adel Nefzi
Journal:  Bioorg Med Chem Lett       Date:  2014-12-08       Impact factor: 2.823

3.  Ethyl 1-(2-hy-droxy-eth-yl)-2-p-tolyl-1H-benzimidazole-5-carboxyl-ate.

Authors:  Natarajan Arumugam; Aisyah Saad Abdul Rahim; Habibah A Wahab; Jia Hao Goh; Hoong-Kun Fun
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-06-05

4.  Synthesis of Tunable Fluorescent Imidazole-Fused Heterocycle Dimers.

Authors:  Qiang Zheng; Xin Li; Katarzyna Kurpiewska; Alexander Dömling
Journal:  Org Lett       Date:  2022-07-13       Impact factor: 6.072
  4 in total

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