| Literature DB >> 12720439 |
Xingyu Jiang1, Jessamine M K Ng, Abraham D Stroock, Stephan K W Dertinger, George M Whitesides.
Abstract
This paper describes a microfluidic immunoassay that is applicable to the parallel determination of multiple analytes and that requires only a few microliters of sample. This assay relies on a microchannel network that achieves serial dilution of analytes; this network replaces manual dilutions employed in traditional immunoassays and enables the analysis of multiple analytes simultaneously. The immunoassay was demonstrated by an analysis of concentrations of antibodies against the HIV viral proteins gp120 and gp41 in human serum.Entities:
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Year: 2003 PMID： 12720439 DOI： 10.1021/ja034566+
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419