Literature DB >> 12716570

[Use of anti-aggregant drugs in primary and secondary cardiovascular prevention in diabetics in town and country in the León area].

J López De La Iglesia1, S Escudero Alvarez, A M González García, A Mencía Mieres, L E García Andrés, B Morán Fernández.   

Abstract

OBJECTIVES: To find how many diabetics should receive anti-aggregant treatment according to the recommendations made since 2001 by the American Diabetes Association (ADA), how many cardiovascular events could be avoided by 100 mg daily of acetylsalicylic acid (ASA), and the cost per event avoided by this measure.
DESIGN: Transversal, descriptive, multi-centre study. SETTING. Primary care. 8 clinics in 5 health districts (3 rural, 1 semi-urban, 4 urban) in the León area. PARTICIPANTS. Diabetics aged 14 or over diagnosed through the ADA criteria since 1997. MAIN MEASUREMENTS. Audit of clinical records, collecting age and sex, the presence of the criteria of the ADA for anti-aggregation, the existence of established cardiovascular disease (CVD) and the anti-aggregant treatment patients receive. RESULTS. 544 diabetics. 97.2% (95% CI, 95.8%-98.6%) comply with anti-aggregation criteria. 101 had established CVD (18.6%; CI, 15.3%-21.9%); 77.2% received anti-aggregants (CI, 73.7%-80.7%).428 had no CVD and did have anti-aggregation criteria (78.7%; CI, 75.3%-82.1%); 9.3% (CI, 6.9%-11.7%) received treatment. CONCLUSIONS. There was basically little follow-up of the ADA anti-aggregation recommendations in primary prevention. Treatment of our diabetics with 100 mg/day of ASA would avoid 7.64 cardiovascular events in five years (CI, 5.56-9.72). The cost per cardiovascular event avoided was 6,625.37 euros (CI, 4821.60-8429.14 euros).

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Year:  2003        PMID: 12716570      PMCID: PMC7681639          DOI: 10.1016/s0212-6567(03)70699-4

Source DB:  PubMed          Journal:  Aten Primaria        ISSN: 0212-6567            Impact factor:   1.137


  15 in total

Review 1.  The sixth (2000) ACCP guidelines for antithrombotic therapy for prevention and treatment of thrombosis. American College of Chest Physicians.

Authors:  J Hirsh; J Dalen; G Guyatt
Journal:  Chest       Date:  2001-01       Impact factor: 9.410

2.  Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III).

Authors: 
Journal:  JAMA       Date:  2001-05-16       Impact factor: 56.272

3.  Prevention of coronary heart disease in clinical practice. Recommendations of the Second Joint Task Force of European and other Societies on coronary prevention.

Authors: 
Journal:  Eur Heart J       Date:  1998-10       Impact factor: 29.983

4.  Aspirin as a therapeutic agent in cardiovascular disease: a statement for healthcare professionals from the American Heart Association.

Authors:  C H Hennekens; M L Dyken; V Fuster
Journal:  Circulation       Date:  1997-10-21       Impact factor: 29.690

5.  ACC/AHA guidelines for the management of patients with acute myocardial infarction. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Acute Myocardial Infarction).

Authors:  T J Ryan; J L Anderson; E M Antman; B A Braniff; N H Brooks; R M Califf; L D Hillis; L F Hiratzka; E Rapaport; B J Riegel; R O Russell; E E Smith; W D Weaver
Journal:  J Am Coll Cardiol       Date:  1996-11-01       Impact factor: 24.094

6.  Aspirin use among adults with diabetes: estimates from the Third National Health and Nutrition Examination Survey.

Authors:  D B Rolka; A Fagot-Campagna; K M Narayan
Journal:  Diabetes Care       Date:  2001-02       Impact factor: 19.112

7.  Prevalence of diabetes and impaired glucose tolerance in Aragón, Spain.

Authors:  B Tamayo-Marco; E Faure-Nogueras; M J Roche-Asensio; E Rubio-Calvo; E Sánchez-Oriz; J A Salvador-Oliván
Journal:  Diabetes Care       Date:  1997-04       Impact factor: 19.112

8.  Aspirin for primary prevention of coronary heart disease: safety and absolute benefit related to coronary risk derived from meta-analysis of randomised trials.

Authors:  P S Sanmuganathan; P Ghahramani; P R Jackson; E J Wallis; L E Ramsay
Journal:  Heart       Date:  2001-03       Impact factor: 5.994

9.  Collaborative overview of randomised trials of antiplatelet therapy--I: Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. Antiplatelet Trialists' Collaboration.

Authors: 
Journal:  BMJ       Date:  1994-01-08

10.  Final report on the aspirin component of the ongoing Physicians' Health Study.

Authors: 
Journal:  N Engl J Med       Date:  1989-07-20       Impact factor: 91.245

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  3 in total

1.  [Finding the right platelet anti-aggregant prescription for type-2 diabetes patients, according to the ADA 2003 criteria].

Authors:  Sandra Raméntol Teys; Vicenta Pujol Blaya; Mónica León de la Fuente; María León-Sanromà
Journal:  Aten Primaria       Date:  2006-10-31       Impact factor: 1.137

2.  [Anti-platelet treatment for all diabetic patients?].

Authors:  José Luis Torres Baile; Guacimara Ortega Sánchez
Journal:  Aten Primaria       Date:  2009-07-22       Impact factor: 1.137

3.  Use of aspirin for primary and secondary prevention of cardiovascular disease in diabetic patients in an ambulatory care setting in Spain.

Authors:  Antoni Sicras-Mainar; Ruth Navarro-Artieda; Javier Rejas-Gutiérrez; Jaime Fernández-de-Bobadilla; Xavier Frías-Garrido; Rafael Ruiz-Riera
Journal:  BMC Fam Pract       Date:  2007-10-17       Impact factor: 2.497

  3 in total

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