Literature DB >> 12714060

Enzymes with extra talents: moonlighting functions and catalytic promiscuity.

Shelley D Copley1.   

Abstract

Recent studies of moonlighting functions and catalytic promiscuity provide insights into the structural and mechanistic bases of these phenomena. Moonlighting proteins that are highlighted include gephyrin, the Neurospora crassa tyrosyl tRNA synthetase, phosphoglucose isomerase, and cytochrome c. New insights into catalytic promiscuity are provided by studies of aminoglycoside kinase (3') type IIIa, tetrachlorohydroquinone dehalogenase, and aldolase antibody 38C2.

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Year:  2003        PMID： 12714060     DOI： 10.1016/s1367-5931(03)00032-2

Source DB:  PubMed          Journal:  Curr Opin Chem Biol        ISSN： 1367-5931            Impact factor:   8.822


  136 in total

1.  The Streptomyces-produced antibiotic fosfomycin is a promiscuous substrate for archaeal isopentenyl phosphate kinase.

Authors:  Mark F Mabanglo; Adrian W R Serohijos; C Dale Poulter
Journal:  Biochemistry       Date:  2012-01-11       Impact factor: 3.162

Review 2.  How versatile are inositol phosphate kinases?

Authors:  Stephen B Shears
Journal:  Biochem J       Date:  2004-01-15       Impact factor: 3.857

3.  Origins of specificity and promiscuity in metabolic networks.

Authors:  Pablo Carbonell; Guillaume Lecointre; Jean-Loup Faulon
Journal:  J Biol Chem       Date:  2011-11-03       Impact factor: 5.157

4.  Ensemble perspective for catalytic promiscuity: calorimetric analysis of the active site conformational landscape of a detoxification enzyme.

Authors:  Matthew T Honaker; Mauro Acchione; John P Sumida; William M Atkins
Journal:  J Biol Chem       Date:  2011-10-14       Impact factor: 5.157

5.  Expression, purification, crystallization and preliminary X-ray studies of Lactobacillus jensenii enolase.

Authors:  Paul T Harris; Kannan Raghunathan; Rachel R Spurbeck; Cindy G Arvidson; Dennis N Arvidson
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2010-07-29

6.  Evolutionary Conservation and Diversification of Puf RNA Binding Proteins and Their mRNA Targets.

Authors:  Gregory J Hogan; Patrick O Brown; Daniel Herschlag
Journal:  PLoS Biol       Date:  2015-11-20       Impact factor: 8.029

7.  Mechanistic insights into the dual activities of the single active site of l-lysine oxidase/monooxygenase from Pseudomonas sp. AIU 813.

Authors:  Duangthip Trisrivirat; Narin Lawan; Pirom Chenprakhon; Daisuke Matsui; Yasuhisa Asano; Pimchai Chaiyen
Journal:  J Biol Chem       Date:  2020-06-11       Impact factor: 5.157

8.  Maize cDNAs expressed in endosperm encode functional farnesyl diphosphate synthase with geranylgeranyl diphosphate synthase activity.

Authors:  Miguel Cervantes-Cervantes; Cynthia E Gallagher; Changfu Zhu; Eleanore T Wurtzel
Journal:  Plant Physiol       Date:  2006-03-31       Impact factor: 8.340

Review 9.  Computer aided enzyme design and catalytic concepts.

Authors:  Maria P Frushicheva; Matthew J L Mills; Patrick Schopf; Manoj K Singh; Ram B Prasad; Arieh Warshel
Journal:  Curr Opin Chem Biol       Date:  2014-05-08       Impact factor: 8.822

10.  Isolation of novel animal cell lines defective in glycerolipid biosynthesis reveals mutations in glucose-6-phosphate isomerase.

Authors:  Jorge F Haller; Conor Smith; Dailan Liu; Hongying Zheng; Keith Tornheim; Gil-Soo Han; George M Carman; Raphael A Zoeller
Journal:  J Biol Chem       Date:  2009-11-10       Impact factor: 5.157
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