Literature DB >> 12714059

Evolution of function in (beta/alpha)8-barrel enzymes.

John A Gerlt1, Frank M Raushel.   

Abstract

The (beta/alpha)(8)-barrel is the most common fold in structurally characterized enzymes. Whether the functionally diverse enzymes that share this fold are the products of either divergent or convergent evolution (or both) is an unresolved question that will probably be answered as the sequence databases continue to expand. Recent work has examined natural, designed, and directed evolution of function in several superfamilies of (beta/alpha)(8)-barrel containing enzymes.

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Year:  2003        PMID： 12714059     DOI： 10.1016/s1367-5931(03)00019-x

Source DB:  PubMed          Journal:  Curr Opin Chem Biol        ISSN： 1367-5931            Impact factor:   8.822


  46 in total

Review 1.  Divergence and convergence in enzyme evolution: parallel evolution of paraoxonases from quorum-quenching lactonases.

Authors:  Mikael Elias; Dan S Tawfik
Journal:  J Biol Chem       Date:  2011-11-08       Impact factor: 5.157

2.  Novel α-glucosidase from human gut microbiome: substrate specificities and their switch.

Authors:  Kemin Tan; Christine Tesar; Rosemarie Wilton; Laura Keigher; Gyorgy Babnigg; Andrzej Joachimiak
Journal:  FASEB J       Date:  2010-06-25       Impact factor: 5.191

Review 3.  Structural and functional dissection of aminocoumarin antibiotic biosynthesis: a review.

Authors:  David M Lawson; Clare E M Stevenson
Journal:  J Struct Funct Genomics       Date:  2012-05-27

4.  Cobinamide production of hydrogen in a homogeneous aqueous photochemical system, and assembly and photoreduction in a (βα)8 protein.

Authors:  Wesley D Robertson; Adonis M Bovell; Kurt Warncke
Journal:  J Biol Inorg Chem       Date:  2013-06-27       Impact factor: 3.358

5.  Mimicking enzyme evolution by generating new (betaalpha)8-barrels from (betaalpha)4-half-barrels.

Authors:  Birte Höcker; Jörg Claren; Reinhard Sterner
Journal:  Proc Natl Acad Sci U S A       Date:  2004-11-11       Impact factor: 11.205

6.  Mapping the structure of folding cores in TIM barrel proteins by hydrogen exchange mass spectrometry: the roles of motif and sequence for the indole-3-glycerol phosphate synthase from Sulfolobus solfataricus.

Authors:  Zhenyu Gu; Jill A Zitzewitz; C Robert Matthews
Journal:  J Mol Biol       Date:  2007-02-20       Impact factor: 5.469

7.  Establishing wild-type levels of catalytic activity on natural and artificial (beta alpha)8-barrel protein scaffolds.

Authors:  Jörg Claren; Christoph Malisi; Birte Höcker; Reinhard Sterner
Journal:  Proc Natl Acad Sci U S A       Date:  2009-02-23       Impact factor: 11.205

8.  Bisubstrate specificity in histidine/tryptophan biosynthesis isomerase from Mycobacterium tuberculosis by active site metamorphosis.

Authors:  Anne V Due; Jochen Kuper; Arie Geerlof; Jens Peter von Kries; Matthias Wilmanns
Journal:  Proc Natl Acad Sci U S A       Date:  2011-02-14       Impact factor: 11.205

9.  Reflections on the catalytic power of a TIM-barrel.

Authors:  John P Richard; Xiang Zhai; M Merced Malabanan
Journal:  Bioorg Chem       Date:  2014-07-11       Impact factor: 5.275

10.  TransCent: computational enzyme design by transferring active sites and considering constraints relevant for catalysis.

Authors:  André Fischer; Nils Enkler; Gerd Neudert; Marco Bocola; Reinhard Sterner; Rainer Merkl
Journal:  BMC Bioinformatics       Date:  2009-02-10       Impact factor: 3.169
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