| Literature DB >> 12711185 |
Andrea Schüssele1, Annette Bauer-Brandl.
Abstract
Flowabilities of six commercially available, direct compression excipients, Emcompress, Fujicalin, Starch 1500, Avicel PH-102, Tablettose 80, and Tablettose 100 were examined according to the technical procedure described in the current European Pharmacopoeia, and with a Sotax Flow Tester. Results revealed unfavourable properties for Fujicalin compared to other substances. Fujicalin, however, appeared macroscopically to be of extremely pronounced free-flowing properties. This contradiction was studied in more detail, proposing to express powder flow in terms of volume per time unit rather than mass per time unit (volume-flowability).Entities:
Mesh:
Substances:
Year: 2003 PMID: 12711185 DOI: 10.1016/s0378-5173(03)00142-x
Source DB: PubMed Journal: Int J Pharm ISSN: 0378-5173 Impact factor: 5.875