Literature DB >> 12710559

Stem cell research in Germany: ethics of healing vs. human dignity.

Fuat S Oduncu1.   

Abstract

On 25 April 2002, the German Parliament has passed a strict new law referring to stem cell research. This law took effect on July 1, 2002. The so-called embryonic Stem Cell Act ("Stammzellgesetz-StZG") permits the import of embryonic stem (ES) cells isolated from surplus lvF-embryos for research reasons. The production itself of ES cells from human blastocysts has been prohibited by the German Embryo Protection Act of 1990, with the exception of the use of ES cells which exist already. The debate on the legitimate use of ES cells escalated, after the main German research funding agency, the Deutsche Forschungsgemeinschaft (DFG), unexpectedly published new guidelines recommending a restricted use of human ES cells for research. Meanwhile, the debate has ethically divided society, political parties, government and church members into a group supporting and a group rejecting ES cell research. The arguments in favour of such a research can be summarized as arguments derived from a new "ethics of healing" calling for a therapeutic imperative, whereas the arguments against can be summarized as arguments violating the fundamental principle of human dignity as they imply the destruction of human embryos. This article will try to present and evaluate various ethical arguments founded on the latest biological and medical data on the potential use of stem cell technologies. It will finally come to the conclusion that ES cell research is opposed to human dignity, since the procedures of isolating ES cells require the destruction and instrumentalization of human embryos. Human embryos are human beings at a very early stage of their development, fully possessing the ability of completing their development. At this very early stage, human embryos are extremely dependent and fragile, and thus vulnerable corporealities. Vulnerability and human dignity demand the protection of the embryo's corporeal integrity. Hence, this essay will try to propagate research with adult stem (AS) cells, a procedure which does not require the destruction of human embryos; with regard to the necessary plasticity, it should be emphasized that AS cells very much resemble ES cells.

Entities:  

Keywords:  Biomedical and Behavioral Research; Genetics and Reproduction; Legal Approach

Mesh:

Year:  2003        PMID: 12710559     DOI: 10.1023/a:1022585217710

Source DB:  PubMed          Journal:  Med Health Care Philos        ISSN: 1386-7423


  28 in total

1.  Dystrophin expression in the mdx mouse restored by stem cell transplantation.

Authors:  E Gussoni; Y Soneoka; C D Strickland; E A Buzney; M K Khan; A F Flint; L M Kunkel; R C Mulligan
Journal:  Nature       Date:  1999-09-23       Impact factor: 49.962

2.  Stem cell research--why is it regarded as a threat? An investigation of the economic and ethical arguments made against research with human embryonic stem cells.

Authors:  P Lachmann
Journal:  EMBO Rep       Date:  2001-03       Impact factor: 8.807

3.  Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells.

Authors:  S H Lee; N Lumelsky; L Studer; J M Auerbach; R D McKay
Journal:  Nat Biotechnol       Date:  2000-06       Impact factor: 54.908

4.  Generalized potential of adult neural stem cells.

Authors:  D L Clarke; C B Johansson; J Wilbertz; B Veress; E Nilsson; H Karlström; U Lendahl; J Frisén
Journal:  Science       Date:  2000-06-02       Impact factor: 47.728

Review 5.  The troublesome concept of the person.

Authors:  B Gordijn
Journal:  Theor Med Bioeth       Date:  1999-08

6.  Stem-cell research delayed by German ethics council.

Authors:  A Abbott
Journal:  Nature       Date:  2001-06-21       Impact factor: 49.962

7.  Viable offspring derived from fetal and adult mammalian cells.

Authors:  I Wilmut; A E Schnieke; J McWhir; A J Kind; K H Campbell
Journal:  Nature       Date:  1997-02-27       Impact factor: 49.962

8.  Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro.

Authors:  B E Reubinoff; M F Pera; C Y Fong; A Trounson; A Bongso
Journal:  Nat Biotechnol       Date:  2000-04       Impact factor: 54.908

9.  Neural progenitors from human embryonic stem cells.

Authors:  B E Reubinoff; P Itsykson; T Turetsky; M F Pera; E Reinhartz; A Itzik; T Ben-Hur
Journal:  Nat Biotechnol       Date:  2001-12       Impact factor: 54.908

10.  Embryonic stem cell lines derived from human blastocysts.

Authors:  J A Thomson; J Itskovitz-Eldor; S S Shapiro; M A Waknitz; J J Swiergiel; V S Marshall; J M Jones
Journal:  Science       Date:  1998-11-06       Impact factor: 47.728

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  5 in total

1.  The future of stem-cell research in Germany. A Delphi study.

Authors:  Peter M Wiedemann; Judith Simon; Silke Schicktanz; Christof Tannert
Journal:  EMBO Rep       Date:  2004-10       Impact factor: 8.807

Review 2.  The tension between self governance and absolute inner worth in Kant's moral philosophy.

Authors:  M Häyry
Journal:  J Med Ethics       Date:  2005-11       Impact factor: 2.903

3.  Abortion, embryonic stem cell research, and waste.

Authors:  David A Jensen
Journal:  Theor Med Bioeth       Date:  2008-04-08

Review 4.  Bone regeneration: stem cell therapies and clinical studies in orthopaedics and traumatology.

Authors:  Enrique Gómez-Barrena; Philippe Rosset; Ingo Müller; Rosaria Giordano; Carmen Bunu; Pierre Layrolle; Yrjö T Konttinen; Frank P Luyten
Journal:  J Cell Mol Med       Date:  2011-06       Impact factor: 5.310

5.  Are human embryos Kantian persons?: Kantian considerations in favor of embryonic stem cell research.

Authors:  Bertha Alvarez Manninen
Journal:  Philos Ethics Humanit Med       Date:  2008-01-31       Impact factor: 2.464

  5 in total

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