Literature DB >> 10834848

Generalized potential of adult neural stem cells.

D L Clarke1, C B Johansson, J Wilbertz, B Veress, E Nilsson, H Karlström, U Lendahl, J Frisén.   

Abstract

The differentiation potential of stem cells in tissues of the adult has been thought to be limited to cell lineages present in the organ from which they were derived, but there is evidence that some stem cells may have a broader differentiation repertoire. We show here that neural stem cells from the adult mouse brain can contribute to the formation of chimeric chick and mouse embryos and give rise to cells of all germ layers. This demonstrates that an adult neural stem cell has a very broad developmental capacity and may potentially be used to generate a variety of cell types for transplantation in different diseases.

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Year:  2000        PMID: 10834848     DOI: 10.1126/science.288.5471.1660

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  157 in total

1.  Direct isolation of human central nervous system stem cells.

Authors:  N Uchida; D W Buck; D He; M J Reitsma; M Masek; T V Phan; A S Tsukamoto; F H Gage; I L Weissman
Journal:  Proc Natl Acad Sci U S A       Date:  2000-12-19       Impact factor: 11.205

Review 2.  A legal and ethical tightrope. Science, ethics and legislation of stem cell research.

Authors:  A Colman; J C Burley
Journal:  EMBO Rep       Date:  2001-01       Impact factor: 8.807

3.  Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model.

Authors:  Lars M Bjorklund; Rosario Sánchez-Pernaute; Sangmi Chung; Therese Andersson; Iris Yin Ching Chen; Kevin St P McNaught; Anna-Liisa Brownell; Bruce G Jenkins; Claes Wahlestedt; Kwang-Soo Kim; Ole Isacson
Journal:  Proc Natl Acad Sci U S A       Date:  2002-01-08       Impact factor: 11.205

4.  From hematopoiesis to neuropoiesis: evidence of overlapping genetic programs.

Authors:  A V Terskikh; M C Easterday; L Li; L Hood; H I Kornblum; D H Geschwind; I L Weissman
Journal:  Proc Natl Acad Sci U S A       Date:  2001-07-03       Impact factor: 11.205

5.  Cardiomyocytes induce endothelial cells to trans-differentiate into cardiac muscle: implications for myocardium regeneration.

Authors:  G Condorelli; U Borello; L De Angelis; M Latronico; D Sirabella; M Coletta; R Galli; G Balconi; A Follenzi; G Frati; M G Cusella De Angelis; L Gioglio; S Amuchastegui; L Adorini; L Naldini; A Vescovi; E Dejana; G Cossu
Journal:  Proc Natl Acad Sci U S A       Date:  2001-09-04       Impact factor: 11.205

6.  Neuroscience from different angles. Student symposium: from genes to thoughts.

Authors:  T Schell; G Testa; S Castagnetti; B Rutz; M Hannus; F Frischknecht
Journal:  EMBO Rep       Date:  2001-06       Impact factor: 8.807

7.  Stem cell identity: life is plastic, it's fantastic!

Authors:  Maneesha S Inamdar
Journal:  J Biosci       Date:  2002-03       Impact factor: 1.826

Review 8.  From teratocarcinomas to embryonic stem cells.

Authors:  Peter W Andrews
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2002-04-29       Impact factor: 6.237

Review 9.  The new stem cell biology: something for everyone.

Authors:  S L Preston; M R Alison; S J Forbes; N C Direkze; R Poulsom; N A Wright
Journal:  Mol Pathol       Date:  2003-04

Review 10.  At the dawn of a new discovery: the potential of breast milk stem cells.

Authors:  Foteini Hassiotou; Peter E Hartmann
Journal:  Adv Nutr       Date:  2014-11-14       Impact factor: 8.701

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