Literature DB >> 1270802

The C5b-9 complex: subunit composition of the classical and alternative pathway-generated complex.

E R Podack, W P Kolb, H J Muller-Eberhard.   

Abstract

The membrane attack complex of complement (C5b-9) is identical in composition regardless of which pathway of activation was instrumental in its formation. Band V protein was consistently a subunit of the soluble complex. Since band V protein is not required for complement-dependent cytolysis, it probably represents a membrane site equivalent in serum of the nascent C5b-9 complex.

Mesh:

Substances:

Year:  1976        PMID: 1270802

Source DB:  PubMed          Journal:  J Immunol        ISSN: 0022-1767            Impact factor:   5.422


  12 in total

1.  Proteolytic transformation of SC5b-9 into an amphiphilic macromolecule resembling the C5b-9 membrane attack complex of complement.

Authors:  S Bhakdi; B Bhakdi-Lehnen; J Tranum-Jensen
Journal:  Immunology       Date:  1979-08       Impact factor: 7.397

Review 2.  Complement: an overview for the clinician.

Authors:  Juan Carlos Varela; Stephen Tomlinson
Journal:  Hematol Oncol Clin North Am       Date:  2015-04-04       Impact factor: 3.722

3.  Membrane attack complex of complement: generation of high-affinity phospholipid binding sites by fusion of five hydrophilic plasma proteins.

Authors:  E R Podack; G Biesecker; H J Müller-Eberhard
Journal:  Proc Natl Acad Sci U S A       Date:  1979-02       Impact factor: 11.205

Review 4.  Now you see me, now you don't: the interaction of Salmonella with innate immune receptors.

Authors:  A Marijke Keestra-Gounder; Renée M Tsolis; Andreas J Bäumler
Journal:  Nat Rev Microbiol       Date:  2015-03-09       Impact factor: 60.633

5.  Complement lysis of human erythrocytes. Differeing susceptibility of two types of paroxysmal nocturnal hemoglobinuria cells to C5b-9.

Authors:  C H Packman; S I Rosenfeld; D E Jenkins; P A Thiem; J P Leddy
Journal:  J Clin Invest       Date:  1979-08       Impact factor: 14.808

6.  Differential mechanisms of complement-mediated neutralization of the closely related paramyxoviruses simian virus 5 and mumps virus.

Authors:  John B Johnson; Gerald A Capraro; Griffith D Parks
Journal:  Virology       Date:  2008-04-28       Impact factor: 3.616

7.  Terminal complement complex in plasma from patients with systemic lupus erythematosus and other glomerular diseases.

Authors:  I Horigome; J Seino; K Sudo; Y Kinoshita; T Saito; K Yoshinaga
Journal:  Clin Exp Immunol       Date:  1987-11       Impact factor: 4.330

8.  Neoantigen of the polymerized ninth component of complement. Characterization of a monoclonal antibody and immunohistochemical localization in renal disease.

Authors:  R J Falk; A P Dalmasso; Y Kim; C H Tsai; J I Scheinman; H Gewurz; A F Michael
Journal:  J Clin Invest       Date:  1983-08       Impact factor: 14.808

9.  C5b-9 dimer: isolation from complement lysed cells and ultrastructural identification with complement-dependent membrane lesions.

Authors:  G Biesecker; E R Podack; C A Halverson; H J Müller-Eberhard
Journal:  J Exp Med       Date:  1979-02-01       Impact factor: 14.307

10.  Human monocyte spreading induced by factor Bb of the alternative pathway of complement activation. A possible role for C5 in monocyte spreading.

Authors:  J S Sundsmo; O Götze
Journal:  J Exp Med       Date:  1981-09-01       Impact factor: 14.307

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.