Literature DB >> 12706259

Expression of MUPP1 protein in mouse brain.

B Sitek1, G Poschmann, K Schmidtke, C Ullmer, L Maskri, M Andriske, C C Stichel, X-R Zhu, H Luebbert.   

Abstract

Localizing cell surface receptors to specific subcellular sites can be crucial for proper functioning. PDZ proteins apparently play central roles in such protein localizations. 5-HT(2C) receptors have previously been shown to interact with MUPP1, a multi PDZ domain protein, in heterologous systems and in rat choroid plexus. We now report the generation and characterization of two independent MUPP1 antisera, which recognise distinct areas of the mouse brain in agreement with previous in-situ hybridization studies. Our results indicate that MUPP1 immunoreactivity co-localizes with 5-HT(2A) or 5-HT(2C) receptor expression in all regions of the mouse brain, including the choroid plexus where 5-HT(2C) receptors are highly enriched.

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Year:  2003        PMID： 12706259     DOI： 10.1016/s0006-8993(03)02338-2

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  11 in total

1.  The neuronal RhoA GEF, Tech, interacts with the synaptic multi-PDZ-domain-containing protein, MUPP1.

Authors:  Marcel A Estévez; Jennifer A Henderson; David Ahn; Xin-Ran Zhu; Gereon Poschmann; Hermann Lübbert; Ruth Marx; Jay M Baraban
Journal:  J Neurochem       Date:  2008-06-04       Impact factor: 5.372

2.  Novel MPDZ/MUPP1 transgenic and knockdown models confirm Mpdz's role in ethanol withdrawal and support its role in voluntary ethanol consumption.

Authors:  Lauren C Milner; Renee L Shirley; Laura B Kozell; Nicole A Walter; Lauren C Kruse; Noboru H Komiyama; Seth G N Grant; Kari J Buck
Journal:  Addict Biol       Date:  2013-10-10       Impact factor: 4.280

Review 3.  Mining the Nav1.7 interactome: Opportunities for chronic pain therapeutics.

Authors:  Lindsey A Chew; Shreya S Bellampalli; Erik T Dustrude; Rajesh Khanna
Journal:  Biochem Pharmacol       Date:  2019-01-27       Impact factor: 5.858

4.  MUPP1 complexes renal K+ channels to alter cell surface expression and whole cell currents.

Authors:  Aleksandra Sindic; Chunfa Huang; An-Ping Chen; Yaxian Ding; William A Miller-Little; Danian Che; Michael F Romero; R Tyler Miller
Journal:  Am J Physiol Renal Physiol       Date:  2009-05-06

5.  Ablation of Cx47 in transgenic mice leads to the loss of MUPP1, ZONAB and multiple connexins at oligodendrocyte-astrocyte gap junctions.

Authors:  Xinbo Li; M Penes; B Odermatt; K Willecke; J I Nagy
Journal:  Eur J Neurosci       Date:  2008-10       Impact factor: 3.386

6.  5-HT2C and GABAB receptors influence handling-induced convulsion severity in chromosome 4 congenic and DBA/2J background strain mice.

Authors:  Matthew T Reilly; Lauren C Milner; Renee L Shirley; John C Crabbe; Kari J Buck
Journal:  Brain Res       Date:  2008-01-18       Impact factor: 3.252

7.  Loss of Mpdz impairs ependymal cell integrity leading to perinatal-onset hydrocephalus in mice.

Authors:  Anja Feldner; M Gordian Adam; Fabian Tetzlaff; Iris Moll; Dorde Komljenovic; Felix Sahm; Tobias Bäuerle; Hiroshi Ishikawa; Horst Schroten; Thomas Korff; Ilse Hofmann; Hartwig Wolburg; Andreas von Deimling; Andreas Fischer
Journal:  EMBO Mol Med       Date:  2017-07       Impact factor: 12.137

8.  Hydrocephalus due to multiple ependymal malformations is caused by mutations in the MPDZ gene.

Authors:  Pascale Saugier-Veber; Florent Marguet; François Lecoquierre; Homa Adle-Biassette; Fabien Guimiot; Sara Cipriani; Sophie Patrier; Marie Brasseur-Daudruy; Alice Goldenberg; Valérie Layet; Yline Capri; Marion Gérard; Thierry Frébourg; Annie Laquerrière
Journal:  Acta Neuropathol Commun       Date:  2017-05-01       Impact factor: 7.801

9.  Murine MPDZ-linked hydrocephalus is caused by hyperpermeability of the choroid plexus.

Authors:  Junning Yang; Claire Simonneau; Robert Kilker; Laura Oakley; Matthew D Byrne; Zuzana Nichtova; Ioana Stefanescu; Fnu Pardeep-Kumar; Sushil Tripathi; Eric Londin; Pascale Saugier-Veber; Belinda Willard; Mathew Thakur; Stephen Pickup; Hiroshi Ishikawa; Horst Schroten; Richard Smeyne; Arie Horowitz
Journal:  EMBO Mol Med       Date:  2019-01       Impact factor: 12.137

10.  The multiple PDZ domain protein Mpdz/MUPP1 regulates opioid tolerance and opioid-induced hyperalgesia.

Authors:  Robin Donaldson; Yuan Sun; De-Yong Liang; Ming Zheng; Peyman Sahbaie; David L Dill; Gary Peltz; Kari J Buck; J David Clark
Journal:  BMC Genomics       Date:  2016-04-29       Impact factor: 3.969
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