Literature DB >> 1270414

Leucine 2,3-aminomutase, an enzyme of leucine catabolism.

J M Poston.   

Abstract

The initial step in the fermentation of leucine to acetate, isobutyrate, and ammonia by Clostridium sporogenes is the B12 coenzyme-dependent conversion of alpha-leucine to beta-leucine (3-amino-4-methylpentanoate). The amino group migration reaction, catalyzed by leucine 2,3-aminomutase, is reversible and is inhibited by intrinsic factor. The enzyme activity has been found in several clostridia, in rat, sheep, rhesus, and African green monkey livers, and in human leukocytes.

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Year:  1976        PMID： 1270414

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  9 in total

1.  Lysine 2,3-aminomutase from Clostridium subterminale SB4: mass spectral characterization of cyanogen bromide-treated peptides and cloning, sequencing, and expression of the gene kamA in Escherichia coli.

Authors:  F J Ruzicka; K W Lieder; P A Frey
Journal:  J Bacteriol       Date:  2000-01       Impact factor: 3.490

2.  Intracellular binding of radioactive hydroxocobalamin to cobalamin-dependent apoenzymes in rat liver.

Authors:  I S Mellman; P Youngdahl-Turner; H F Willard; L E Rosenberg
Journal:  Proc Natl Acad Sci U S A       Date:  1977-03       Impact factor: 11.205

3.  A model of Costeff Syndrome reveals metabolic and protective functions of mitochondrial OPA3.

Authors:  Wuhong Pei; Lisa E Kratz; Isa Bernardini; Raman Sood; Tohei Yokogawa; Heidi Dorward; Carla Ciccone; Richard I Kelley; Yair Anikster; Harold A Burgess; Marjan Huizing; Benjamin Feldman
Journal:  Development       Date:  2010-08-01       Impact factor: 6.868

4.  Changes in chemical composition of a decomposing aquatic macrophyte,Lemna paucicostata.

Authors:  R L Patience; P R Sterry; J D Thomas
Journal:  J Chem Ecol       Date:  1983-07       Impact factor: 2.626

5.  Cobalamins and cobalamin-dependent enzymes in Candida utilis.

Authors:  J M Poston; B A Hemmings
Journal:  J Bacteriol       Date:  1979-12       Impact factor: 3.490

6.  The mechanism of cobalamin-dependent rearrangements.

Authors:  J S Krouwer; B M Babior
Journal:  Mol Cell Biochem       Date:  1977-04-12       Impact factor: 3.396

7.  Nitrous oxide has multiple deleterious effects on cobalamin metabolism and causes decreases in activities of both mammalian cobalamin-dependent enzymes in rats.

Authors:  H Kondo; M L Osborne; J F Kolhouse; M J Binder; E R Podell; C S Utley; R S Abrams; R H Allen
Journal:  J Clin Invest       Date:  1981-05       Impact factor: 14.808

8.  The atu and liu clusters are involved in the catabolic pathways for acyclic monoterpenes and leucine in Pseudomonas aeruginosa.

Authors:  J A Aguilar; A N Zavala; C Díaz-Pérez; C Cervantes; A L Díaz-Pérez; J Campos-García
Journal:  Appl Environ Microbiol       Date:  2006-03       Impact factor: 4.792

9.  Interconversion of valine and leucine by Clostridium sporogenes.

Authors:  D J Monticello; R N Costilow
Journal:  J Bacteriol       Date:  1982-11       Impact factor: 3.490
  9 in total

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