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Literature DB >> 12692252

Hepatitis B virus-mediated changes of apolipoprotein mRNA abundance in cultured hepatoma cells.

Pamela A Norton¹, Qiaoke Gong, Anand S Mehta, Xuanyong Lu, Timothy M Block.

Abstract

An inverse correlation between hepatitis B virus (HBV) and steady-state levels of apolipoprotein AI and CIII mRNAs was observed in two hepatoma cell lines. Analysis of a third line containing an inducible viral genome implicated viral pregenomic RNA in apolipoprotein mRNA reduction. We conclude that HBV alters infected cells despite the absence of overt cytopathogenicity.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 2003 PMID： 12692252 PMCID： PMC153946 DOI： 10.1128/jvi.77.9.5503-5506.2003

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

18 in total

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11 in total

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Journal: World J Gastroenterol Date: 2016-01-07 Impact factor: 5.742

2. Low plasma apolipoprotein A-I level is not a reliable marker of fibrosis in children with chronic hepatitis B.

Authors: Mukadder-Ayse Selimoglu; Rasit-Vural Yagcl; Gül Yüce
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Authors: Xiaohui Zhao; Drishti Shah; Usha Sambamoorthi
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Review 5. Transaminase Elevations during Treatment of Chronic Hepatitis B Infection: Safety Considerations and Role in Achieving Functional Cure.

Authors: Andrew Vaillant
Journal: Viruses Date: 2021-04-23 Impact factor: 5.048