Literature DB >> 12691860

Is high concentration of serum lipids a risk factor for Achilles tendon rupture?

Taner Ozgurtas1, Cemil Yildiz, Muhittin Serdar, Sabri Atesalp, Turker Kutluay.   

Abstract

BACKGROUND: The incidence of the Achilles tendon ruptures (ATR) seems to be increasing due to changes in life style and intensified sports activities in recent years. Intrinsic and extrinsic factors have been implicated as predisposing risk factors to rupture. The purpose of this study was to investigate whether the high serum lipid concentrations could be an intrinsic factor in patient with complete ruptures of Achilles tendon.
METHODS: The data were collected from the records of 47 patients with complete rupture of Achilles and the control group consisted of 26 subjects.
RESULTS: Total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) concentrations of the patients with ATR were higher (p<0.001), and their high-density lipoprotein cholesterol (HDL-C) was lower than the control group (p<0.05). Moreover, the concentrations of triglyceride (TG) and very low-density lipoprotein cholesterol (VLDL-C) were significantly higher than controls (p<0.05).
CONCLUSIONS: The causes of ATR are multifactorial and still unclear. However, high serum lipid concentrations might be considered, as a predisposing factor in patients with complete rupture of Achilles tendon and further investigations with larger groups would be better.

Entities:  

Mesh:

Substances:

Year:  2003        PMID: 12691860     DOI: 10.1016/s0009-8981(03)00075-5

Source DB:  PubMed          Journal:  Clin Chim Acta        ISSN: 0009-8981            Impact factor:   3.786


  21 in total

Review 1.  Exploring the role of hypercholesterolemia in tendon health and repair.

Authors:  Michael W Hast; Joseph A Abboud; Louis J Soslowsky
Journal:  Muscles Ligaments Tendons J       Date:  2014-11-17

2.  Emerging ideas: the effect of hypercholesterolemia on tendons.

Authors:  Joseph A Abboud; David P Beason; Louis J Soslowsky
Journal:  Clin Orthop Relat Res       Date:  2010-12-03       Impact factor: 4.176

3.  The effect of hypercholesterolemia on rotator cuff disease.

Authors:  Joseph A Abboud; Jae S Kim
Journal:  Clin Orthop Relat Res       Date:  2010-06       Impact factor: 4.176

4.  Rat rotator cuff tendon-to-bone healing properties are adversely affected by hypercholesterolemia.

Authors:  David P Beason; Jennica J Tucker; Chang Soo Lee; Lena Edelstein; Joseph A Abboud; Louis J Soslowsky
Journal:  J Shoulder Elbow Surg       Date:  2013-12-02       Impact factor: 3.019

5.  Hypercholesterolemia increases supraspinatus tendon stiffness and elastic modulus across multiple species.

Authors:  David P Beason; Jason E Hsu; Stephanie M Marshall; Allison L McDaniel; Ryan E Temel; Joseph A Abboud; Louis J Soslowsky
Journal:  J Shoulder Elbow Surg       Date:  2012-09-13       Impact factor: 3.019

6.  Tendon, tendon healing, hyperlipidemia and statins.

Authors:  Irfan Esenkaya; Koray Unay
Journal:  Muscles Ligaments Tendons J       Date:  2012-04-01

7.  What is the role of systemic conditions and options for manipulation of bone formation and bone resorption in rotator cuff tendon healing and repair?

Authors:  Simon Lee; Jonathan Gumucio; Christopher Mendias; Asheesh Bedi
Journal:  Tech Shoulder Elb Surg       Date:  2017-09

8.  Obesity Increases the Risk of Tendinopathy, Tendon Tear and Rupture, and Postoperative Complications: A Systematic Review of Clinical Studies.

Authors:  Marina Macchi; Matteo Spezia; Silvia Elli; Gabriele Schiaffini; Emanuele Chisari
Journal:  Clin Orthop Relat Res       Date:  2020-08       Impact factor: 4.755

9.  Lipids, adiposity and tendinopathy: is there a mechanistic link? Critical review.

Authors:  Alex Scott; Johannes Zwerver; Navi Grewal; Agnetha de Sa; Thuraya Alktebi; David J Granville; David A Hart
Journal:  Br J Sports Med       Date:  2014-12-08       Impact factor: 13.800

10.  Role of serum fibrinogen levels in patients with rotator cuff tears.

Authors:  Umile Giuseppe Longo; Stefano Petrillo; Alessandra Berton; Filippo Spiezia; Mattia Loppini; Nicola Maffulli; Vincenzo Denaro
Journal:  Int J Endocrinol       Date:  2014-04-10       Impact factor: 3.257

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.