Literature DB >> 12688733

Enzymatic profiling system in a small-molecule microarray.

Qing Zhu1, Mahesh Uttamchandani, Dongbo Li, Marie L Lesaicherre, Shao Q Yao.   

Abstract

[reaction: see text] We have developed a microarray-based strategy for detection of three major classes of hydrolytic enzymes on the basis of their catalytic activities. This enables the sensitive detection of proteins not merely by their bindings but rather by their enzymatic activities. This may provide a valuable tool for screening, identification, and characterization of new enzymes in a high-throughput fashion.

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Year:  2003        PMID： 12688733     DOI： 10.1021/ol034233h

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  10 in total

Review 1.  Application of microarrays in high-throughput enzymatic profiling.

Authors:  Mahesh Uttamchandani; Xuan Huang; Grace Y J Chen; Lay-Pheng Tan; Shao Q Yao
Journal:  Mol Biotechnol       Date:  2004-11       Impact factor: 2.695

2.  Two-Step Enzymatic Modification of Solid-Supported Bergenin in Aqueous and Organic Media.

Authors:  Umar Akbar; Dong-Sik Shin; Elizabeth Schneider; Jonathan S Dordick; Douglas S Clark
Journal:  Tetrahedron Lett       Date:  2010-02-24       Impact factor: 2.415

Review 3.  Deciphering enzyme function using peptide arrays.

Authors:  Alexandra Thiele; Gabriele I Stangl; Mike Schutkowski
Journal:  Mol Biotechnol       Date:  2011-11       Impact factor: 2.695

4.  Microarrays of small molecules embedded in biodegradable polymers for use in mammalian cell-based screens.

Authors:  Steve N Bailey; David M Sabatini; Brent R Stockwell
Journal:  Proc Natl Acad Sci U S A       Date:  2004-11-08       Impact factor: 11.205

5.  Fluorous-based Peptide Microarrays for Protease Screening.

Authors:  Beatrice Y M Collet; Tadamichi Nagashima; Marvin S Yu; Nicola L B Pohl
Journal:  J Fluor Chem       Date:  2009-11-01       Impact factor: 2.050

Review 6.  Recent advances in gel-based proteome profiling techniques.

Authors:  Yi Hu; Xuan Huang; Grace Y J Chen; Shao Q Yao
Journal:  Mol Biotechnol       Date:  2004-09       Impact factor: 2.695

Review 7.  Protein microarrays: novel developments and applications.

Authors:  Luis Berrade; Angie E Garcia; Julio A Camarero
Journal:  Pharm Res       Date:  2010-11-30       Impact factor: 4.200

8.  Development of an iron-selective antioxidant probe with protective effects on neuronal function.

Authors:  Olimpo García-Beltrán; Natalia P Mena; Pabla Aguirre; Germán Barriga-González; Antonio Galdámez; Edgar Nagles; Tatiana Adasme; Cecilia Hidalgo; Marco T Núñez
Journal:  PLoS One       Date:  2017-12-11       Impact factor: 3.240

9.  Membrane protein channels equipped with a cleavable linker for inducing catalysis inside nanocompartments.

Authors:  Luisa Zartner; Viviana Maffeis; Cora-Ann Schoenenberger; Ionel Adrian Dinu; Cornelia G Palivan
Journal:  J Mater Chem B       Date:  2021-11-10       Impact factor: 6.331

10.  Synthesis and characterisation of PEG-peptide surfaces for proteolytic enzyme detection.

Authors:  Roza Trzcinska; Piotr Suder; Anna Bodzon-Kulakowska; Magdalena Skalska; Andrzej Marcinkowski; Jerzy Kubacki; Roman Pedrys; Jerzy Silberring; Andrzej Dworak; Barbara Trzebicka
Journal:  Anal Bioanal Chem       Date:  2013-06-20       Impact factor: 4.142
  10 in total

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