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Literature DB >> 12682280

Therapy for macular degeneration: insights from acne.

Janet R Sparrow¹.

Abstract

Mesh：

Substances：

Year: 2003 PMID： 12682280 PMCID： PMC153554 DOI： 10.1073/pnas.1031478100

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

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32 in total

1. A2E, a lipofuscin fluorophore, in human retinal pigmented epithelial cells in culture.

Authors: J R Sparrow; C A Parish; M Hashimoto; K Nakanishi
Journal: Invest Ophthalmol Vis Sci Date: 1999-11 Impact factor: 4.799

2. Blue light-induced apoptosis of A2E-containing RPE: involvement of caspase-3 and protection by Bcl-2.

Authors: J R Sparrow; B Cai
Journal: Invest Ophthalmol Vis Sci Date: 2001-05 Impact factor: 4.799

3. The Rpe65 Leu450Met variation increases retinal resistance against light-induced degeneration by slowing rhodopsin regeneration.

Authors: A Wenzel; C E Reme; T P Williams; F Hafezi; C Grimm
Journal: J Neurosci Date: 2001-01-01 Impact factor: 6.167

4. Biosynthesis of a major lipofuscin fluorophore in mice and humans with ABCR-mediated retinal and macular degeneration.

Authors: N L Mata; J Weng; G H Travis
Journal: Proc Natl Acad Sci U S A Date: 2000-06-20 Impact factor: 11.205

5. The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells.

Authors: J R Sparrow; K Nakanishi; C A Parish
Journal: Invest Ophthalmol Vis Sci Date: 2000-06 Impact factor: 4.799

6. A QTL on distal chromosome 3 that influences the severity of light-induced damage to mouse photoreceptors.

Authors: M Danciger; M T Matthes; D Yasamura; N B Akhmedov; T Rickabaugh; S Gentleman; T M Redmond; M M La Vail; D B Farber
Journal: Mamm Genome Date: 2000-06 Impact factor: 2.957

7. The biosynthesis of A2E, a fluorophore of aging retina, involves the formation of the precursor, A2-PE, in the photoreceptor outer segment membrane.

Authors: J Liu; Y Itagaki; S Ben-Shabat; K Nakanishi; J R Sparrow
Journal: J Biol Chem Date: 2000-09-22 Impact factor: 5.157

8. Age-related macular degeneration. The lipofusion component N-retinyl-N-retinylidene ethanolamine detaches proapoptotic proteins from mitochondria and induces apoptosis in mammalian retinal pigment epithelial cells.

Authors: M Suter; C Remé; C Grimm; A Wenzel; M Jäättela; P Esser; N Kociok; M Leist; C Richter
Journal: J Biol Chem Date: 2000-12-15 Impact factor: 5.157

9. Isolation and one-step preparation of A2E and iso-A2E, fluorophores from human retinal pigment epithelium.

Authors: C A Parish; M Hashimoto; K Nakanishi; J Dillon; J Sparrow
Journal: Proc Natl Acad Sci U S A Date: 1998-12-08 Impact factor: 11.205

10. Inhibition of the visual cycle in vivo by 13-cis retinoic acid protects from light damage and provides a mechanism for night blindness in isotretinoin therapy.

Authors: P A Sieving; P Chaudhry; M Kondo; M Provenzano; D Wu; T J Carlson; R A Bush; D A Thompson
Journal: Proc Natl Acad Sci U S A Date: 2001-02-06 Impact factor: 11.205

10 in total

1. How much blue light should an IOL transmit?

Authors: M A Mainster; J R Sparrow
Journal: Br J Ophthalmol Date: 2003-12 Impact factor: 4.638

2. Rpe65 Leu450Met variant is associated with reduced levels of the retinal pigment epithelium lipofuscin fluorophores A2E and iso-A2E.

Authors: So Ra Kim; Nathan Fishkin; Jian Kong; Koji Nakanishi; Rando Allikmets; Janet R Sparrow
Journal: Proc Natl Acad Sci U S A Date: 2004-07-26 Impact factor: 11.205

Review 3. The retinal pigment epithelium in health and disease.

Authors: J R Sparrow; D Hicks; C P Hamel
Journal: Curr Mol Med Date: 2010-12 Impact factor: 2.222

Review 4. Aging of perennial cells and organ parts according to the programmed aging paradigm.

Authors: Giacinto Libertini; Nicola Ferrara
Journal: Age (Dordr) Date: 2016-03-08

5. Altered retinoid homeostasis catalyzed by a nicotine metabolite: implications in macular degeneration and normal development.

Authors: Andrew P Brogan; Tobin J Dickerson; Grant E Boldt; Kim D Janda
Journal: Proc Natl Acad Sci U S A Date: 2005-07-13 Impact factor: 11.205

6. Light filtering in a retinal pigment epithelial cell culture model.

Authors: Jilin Zhou; Janet R Sparrow
Journal: Optom Vis Sci Date: 2011-06 Impact factor: 1.973

7. Immunochemical recognition of A2E, a pigment in the lipofuscin of retinal pigment epithelial cells.

Authors: Chandima Abeywickrama; Hiroko Matsuda; Steffen Jockusch; Jilin Zhou; Young P Jang; Bi-Xing Chen; Yasuhiro Itagaki; Bernard F Erlanger; Koji Nakanishi; Nicholas J Turro; Janet R Sparrow
Journal: Proc Natl Acad Sci U S A Date: 2007-09-05 Impact factor: 11.205