Literature DB >> 12681240

Platelet purinergic receptors.

Satya P Kunapuli1, Robert T Dorsam, Soochong Kim, Todd M Quinton.   

Abstract

Activation of P2Y(1) and P2Y(12) receptors, through secreted ADP that is stimulated by agonists such as thrombin, thromboxane and collagen, is a major mechanism of platelet activation. P2X(1) receptors also participate in platelet shape change and potentiation of calcium mobilization. The cloning of the P2Y(12) receptor and its subsequent knockout in mice promises further understanding of its downstream signaling events.

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Year:  2003        PMID： 12681240     DOI： 10.1016/s1471-4892(03)00007-9

Source DB:  PubMed          Journal:  Curr Opin Pharmacol        ISSN： 1471-4892            Impact factor:   5.547


  29 in total

1.  Sensitivity limits for voltage control of P2Y receptor-evoked Ca2+ mobilization in the rat megakaryocyte.

Authors:  Juan Martinez-Pinna; Gwen Tolhurst; Iman S Gurung; Jamie I Vandenberg; Martyn P Mahaut-Smith
Journal:  J Physiol       Date:  2003-11-28       Impact factor: 5.182

Review 2.  Central role of the P2Y12 receptor in platelet activation.

Authors:  Robert T Dorsam; Satya P Kunapuli
Journal:  J Clin Invest       Date:  2004-02       Impact factor: 14.808

Review 3.  Functions of heteromeric association between adenosine and P2Y receptors.

Authors:  Hiroyasu Nakata; Kazuaki Yoshioka; Toshio Kamiya; Hirofumi Tsuga; Koshi Oyanagi
Journal:  J Mol Neurosci       Date:  2005       Impact factor: 3.444

Review 4.  P2 receptors: intracellular signaling.

Authors:  Laurie Erb; Zhongji Liao; Cheikh I Seye; Gary A Weisman
Journal:  Pflugers Arch       Date:  2006-04-04       Impact factor: 3.657

Review 5.  The GPIIb/IIIa (integrin alphaIIbbeta3) odyssey: a technology-driven saga of a receptor with twists, turns, and even a bend.

Authors:  Barry S Coller; Sanford J Shattil
Journal:  Blood       Date:  2008-10-15       Impact factor: 22.113

6.  P2Y12 Receptor Modulates Sepsis-Induced Inflammation.

Authors:  Elisabetta Liverani; Mario C Rico; Alexander Y Tsygankov; Laurie E Kilpatrick; Satya P Kunapuli
Journal:  Arterioscler Thromb Vasc Biol       Date:  2016-04-07       Impact factor: 8.311

Review 7.  Regulators of G-protein signaling and their Gα substrates: promises and challenges in their use as drug discovery targets.

Authors:  Adam J Kimple; Dustin E Bosch; Patrick M Giguère; David P Siderovski
Journal:  Pharmacol Rev       Date:  2011-07-07       Impact factor: 25.468

Review 8.  The role of P2Y₁₂ receptor and activated platelets during inflammation.

Authors:  Elisabetta Liverani; Laurie E Kilpatrick; Alexander Y Tsygankov; Satya P Kunapuli
Journal:  Curr Drug Targets       Date:  2014       Impact factor: 3.465

Review 9.  Aspirin and clopidogrel hyporesponsiveness and nonresponsiveness in patients with coronary artery stenting.

Authors:  Rakesh K Sharma; Hanumanth K Reddy; Vibhuti N Singh; Rohit Sharma; Donald J Voelker; Girish Bhatt
Journal:  Vasc Health Risk Manag       Date:  2009-11-16

Review 10.  Dysfunctional platelet membrane receptors: from humans to mice.

Authors:  Jerry Ware
Journal:  Thromb Haemost       Date:  2004-09       Impact factor: 5.249
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